PMID- 25675666
OWN - NLM
STAT- MEDLINE
DCOM- 20150304
LR  - 20150213
IS  - 1781-782X (Print)
IS  - 1781-782X (Linking)
VI  - 10
IP  - 3
DP  - 2014
TI  - Effects of systemic steroids on life quality in sinonasal polyposis.
PG  - 203-8
AB  - OBJECTIVE: To determine the effectiveness of short-term glucocorticoid therapy on 
      nasal polyposis. METHODOLOGY: A total of 60 patients with sinonasal polyposis 
      were given oral glucocorticoid therapy (1 mg/kg) for 20 days. Patient symptoms 
      were evaluated with the Sino-Nasal Outcome Test 20 (SNOT-20). Computerized 
      tomography (CT) images of the paranasal sinus were acquired before and after 
      treatment and were evaluated with the Kennedy scoring system. RESULTS: Evaluation 
      of paranasal CTs showed complete disease resolution in 15 patients and partial 
      disease resolution in 25 patients. Patients with complete and partial 
      resolutions,based on CT images, exhibited significant decreases in disease 
      stages. Statistical analysis revealed a significant change in the SNOT-20 results 
      (P < 0.01). There were no statistically significant differences among the 
      evaluations based on the paranasal sinus CTs, the SNOT-20, and the SNOT-20 
      combined with a subjective selection of the five most disturbing symptoms 
      (SNOT-20(+5)) (P > 0.05). CONCLUSION: The results showed a strong correlation 
      between radiological changes and improvements in quality of life, assessed with 
      the SNOT-20 or the SNOT-20(+5).
FAU - Berkiten, G
AU  - Berkiten G
FAU - Salturk, Z
AU  - Salturk Z
FAU - Topaloglu, I
AU  - Topaloglu I
LA  - eng
PT  - Journal Article
PL  - Belgium
TA  - B-ENT
JT  - B-ENT
JID - 101247842
RN  - 0 (Glucocorticoids)
RN  - X4W7ZR7023 (Methylprednisolone)
SB  - IM
MH  - Administration, Oral
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Female
MH  - Glucocorticoids/*therapeutic use
MH  - Humans
MH  - Male
MH  - Methylprednisolone/*therapeutic use
MH  - Middle Aged
MH  - Nasal Polyps/*drug therapy/psychology
MH  - *Quality of Life
MH  - Young Adult
EDAT- 2015/02/14 06:00
MHDA- 2015/03/05 06:00
CRDT- 2015/02/14 06:00
PHST- 2015/02/14 06:00 [entrez]
PHST- 2015/02/14 06:00 [pubmed]
PHST- 2015/03/05 06:00 [medline]
PST - ppublish
SO  - B-ENT. 2014;10(3):203-8.