PMID- 25680742
OWN - NLM
STAT- MEDLINE
DCOM- 20160115
LR  - 20150421
IS  - 1934-7243 (Electronic)
IS  - 0736-9387 (Linking)
VI  - 65
IP  - 1
DP  - 2015 Apr
TI  - Greater functional connectivity between reading and error-detection regions 
      following training with the reading acceleration program in children with reading 
      difficulties.
PG  - 1-23
LID - 10.1007/s11881-015-0096-9 [doi]
AB  - The Reading Acceleration Program is a computerized program that improves reading 
      and the activation of the error-detection mechanism in individuals with reading 
      difficulty (RD) and typical readers (TRs). The current study aims to find the 
      neural correlates for this effect in English-speaking 8-12-year-old children with 
      RD and TRs using a functional connectivity analysis. Functional magnetic 
      resonance imaging data were collected during a lexical decision task before and 
      after 4 weeks of training with the program, together with reading and executive 
      functions measures. Results indicated improvement in reading, visual attention, 
      and speed of processing in children with RD. Following training, greater 
      functional connectivity was observed between the left fusiform gyrus and the 
      right anterior cingulate cortex in children with RD and between the left fusiform 
      gyrus and the left anterior cingulate cortex in TRs. The change in functional 
      connectivity after training was correlated with increased behavioral scores for 
      word reading and visual attention in both groups. The results support previous 
      findings of improved monitoring and mental lexicon after training with the 
      Reading Acceleration Program in children with RD and TRs. The differences in 
      laterality of the anterior cingulate cortex in children with RD and the 
      presumable role of the cingulo-opercular control network in language processing 
      are discussed.
FAU - Horowitz-Kraus, Tzipi
AU  - Horowitz-Kraus T
AD  - Pediatric Neuroimaging Research Consortium, Cincinnati Children's Hospital 
      Medical Center, Cincinnati, OH, USA, Tzipi.Horowitz-Kraus@cchmc.org.
FAU - Holland, Scott K
AU  - Holland SK
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20150214
PL  - United States
TA  - Ann Dyslexia
JT  - Annals of dyslexia
JID - 8406611
SB  - IM
MH  - Brain Mapping/methods
MH  - Child
MH  - Dyslexia/diagnosis/*metabolism/therapy
MH  - Education/*methods/trends
MH  - Female
MH  - Gyrus Cinguli/*metabolism/pathology
MH  - Humans
MH  - Magnetic Resonance Imaging/methods
MH  - Male
MH  - Neural Pathways/metabolism/pathology
MH  - Photic Stimulation/methods
MH  - *Reading
MH  - Temporal Lobe/*metabolism/pathology
EDAT- 2015/02/15 06:00
MHDA- 2016/01/16 06:00
CRDT- 2015/02/15 06:00
PHST- 2014/09/19 00:00 [received]
PHST- 2015/01/20 00:00 [accepted]
PHST- 2015/02/15 06:00 [entrez]
PHST- 2015/02/15 06:00 [pubmed]
PHST- 2016/01/16 06:00 [medline]
AID - 10.1007/s11881-015-0096-9 [doi]
PST - ppublish
SO  - Ann Dyslexia. 2015 Apr;65(1):1-23. doi: 10.1007/s11881-015-0096-9. Epub 2015 Feb 
      14.