PMID- 25682459
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20191120
IS  - 2078-2101 (Print)
IS  - 2078-2101 (Linking)
VI  - 1
IP  - 17
DP  - 2015 Jan
TI  - Primary Mixed Cellularity Classical Hodgkin lymphoma of the Lumbar spine - An 
      unusual presentation.
PG  - 88-91
AB  - Primary spinal epidural lymphoma (PSEL) is a subset of lymphoma. For the 
      diagnosis of PSEL there should be no other recognizable sites of lymphoma other 
      than the spine at the time of diagnosis. The incidence of this subset of 
      lymphomas is very low. Hodgkin lymphoma (HL) usually presents with painless 
      enlargement of peripheral lymph nodes and only a small percentage arises from 
      extra nodal regions.Very few patients with HL develops spinal cord compression 
      due to an epidural tumor at some time during the course of their disease. But 
      patients with HL presenting with isolated primary involvement of the epidural 
      spinal region is very rare with very few reports available in the literature. 
      CASE: A 19-year-old male presented to the local hospital with history of low back 
      pain for almost one year. An initial biopsy was non-contributory and was reported 
      as showing inflammatory change. The patient was empirically started on 
      antituberculosis medication but his condition worsened and within weeks he 
      developed paraplegia. MRI of the spine showed a large paraspinal mass with 
      compression of L1 vertebral body. Urgent surgical decompression was done and 
      final histopathology showed a mixed cellularity classical Hodgkin lymphoma 
      (MCCHL). Systemic work-up did not show evidence of nodal disease. Following 
      surgery, he received chemotherapy. CONCLUSION: We report this case because of the 
      unusual presentation of HL as a primary spinal mass. We would also like to 
      highlight that apart from common causes, a differential diagnosis of HL should 
      also be entertained while dealing with spinal masses. Otherwise diagnosis can be 
      missed leading to delay in treatment and complications.
FAU - Anila, K R
AU  - Anila KR
AD  - Dept. of Pathology, Regional Cancer Centre, Thiruvananthapuram, Kerala, India.
FAU - Nair, R A
AU  - Nair RA
AD  - Dept. of Pathology, Regional Cancer Centre, Thiruvananthapuram, Kerala, India.
FAU - Prem, S
AU  - Prem S
AD  - Dept. of Medical Oncology, Regional Cancer Centre, Thiruvananthapuram, Kerala, 
      India.
FAU - Ramachandran, K
AU  - Ramachandran K
AD  - Dept. of Medical Oncology, Regional Cancer Centre, Thiruvananthapuram, Kerala, 
      India.
LA  - eng
PT  - Journal Article
PL  - Kuwait
TA  - Gulf J Oncolog
JT  - The Gulf journal of oncology
JID - 101500911
SB  - IM
EDAT- 2015/02/16 06:00
MHDA- 2015/02/16 06:01
CRDT- 2015/02/16 06:00
PHST- 2014/10/14 00:00 [accepted]
PHST- 2015/02/16 06:00 [entrez]
PHST- 2015/02/16 06:00 [pubmed]
PHST- 2015/02/16 06:01 [medline]
PST - ppublish
SO  - Gulf J Oncolog. 2015 Jan;1(17):88-91.