PMID- 2568529
OWN - NLM
STAT- MEDLINE
DCOM- 19890823
LR  - 20220409
IS  - 0140-6736 (Print)
IS  - 0140-6736 (Linking)
VI  - 2
IP  - 8656
DP  - 1989 Jul 22
TI  - APACHE-II score for assessment and monitoring of acute pancreatitis.
PG  - 201-5
AB  - The value of the Acute Physiology and Chronic Health Enquiry (APACHE-II) score, 
      the Simplified Acute Physiology score, and the Medical Research Council (MRC) 
      sepsis score were compared with clinical assessment and Ranson and Imrie scores 
      in the evaluation and monitoring of acute pancreatitis in 290 attacks. Attacks 
      were graded mild (231) if uncomplicated, or severe (59) when major organ failure 
      or a pancreatic collection occurred. Only APACHE-II scores were available at the 
      time of admission; they correctly predicted outcome in 77% of attacks and 
      identified 63% of severe attacks, compared with 44% achieved by clinical 
      assessment. After 48 h, APACHE-II was most accurate, and correctly predicted 
      outcome in 88% of attacks, compared with 69% for Ranson and 84% for Imrie scores. 
      APACHE-II predicted 73% of pancreatic collections at 48 h, compared with 65% for 
      Ranson and 58% for Imrie scores. In acute pancreatitis, APACHE-II may facilitate 
      rapid selection of patients for intensive therapy or clinical trials, improve 
      comparison between groups of patients, and indicate that a pancreatic collection 
      is probable.
FAU - Larvin, M
AU  - Larvin M
AD  - University Department of Surgery, General Infirmary, Leeds.
FAU - McMahon, M J
AU  - McMahon MJ
LA  - eng
PT  - Clinical Trial
PT  - Comparative Study
PT  - Controlled Clinical Trial
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - Lancet
JT  - Lancet (London, England)
JID - 2985213R
SB  - IM
CIN - Lancet. 1989 Sep 23;2(8665):738. PMID: 2570979
MH  - Abscess/diagnosis
MH  - Acute Disease
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Exudates and Transudates
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Pancreatic Pseudocyst/diagnosis
MH  - Pancreatitis/*classification/diagnosis/etiology
MH  - Physical Examination
MH  - Predictive Value of Tests
MH  - Sensitivity and Specificity
EDAT- 1989/07/22 00:00
MHDA- 1989/07/22 00:01
CRDT- 1989/07/22 00:00
PHST- 1989/07/22 00:00 [pubmed]
PHST- 1989/07/22 00:01 [medline]
PHST- 1989/07/22 00:00 [entrez]
AID - S0140-6736(89)90381-4 [pii]
AID - 10.1016/s0140-6736(89)90381-4 [doi]
PST - ppublish
SO  - Lancet. 1989 Jul 22;2(8656):201-5. doi: 10.1016/s0140-6736(89)90381-4.