PMID- 25688817
OWN - NLM
STAT- MEDLINE
DCOM- 20151203
LR  - 20150218
IS  - 1479-828X (Electronic)
IS  - 0004-8666 (Linking)
VI  - 55
IP  - 1
DP  - 2015 Feb
TI  - Exercise in pregnancy does not alter gestational weight gain, MCP-1 or leptin in 
      obese women.
PG  - 27-33
LID - 10.1111/ajo.12300 [doi]
AB  - BACKGROUND: Increasing physical activity in pregnancy may improve pregnancy 
      outcomes for obese women. Exercise could reduce gestational weight gain, improve 
      the maternal circulating lipid profile as well as alter leptin, Interleukin-8 
      (IL-8) and Monocyte Chemoattractant Protein-1 (MCP-1) levels. AIM: The aim of 
      this study was to investigate the effects of exercise on gestational weight gain, 
      maternal circulating lipids, IL-8, MCP-1 and leptin levels in obese pregnant 
      women. MATERIALS AND METHODS: The analysis was performed in the 35 obese women 
      enrolled in the pilot BAMBINO randomised controlled trial who provided blood 
      samples at 12- and 28-weeks gestation. Women in the exercise intervention arm 
      received an individualised exercise plan. Blood samples, exercise diary and 
      pedometer data were obtained at 12-, 20-, 28- and 36-weeks' gestation. Cord blood 
      was obtained at delivery. RESULTS: Women in the exercise arm exercised more than 
      those in the control arm (P = 0.038). There was no difference in gestational 
      weight gain, excess gestational weight gain, MCP-1 and leptin levels between 
      women in the exercise intervention (n = 19) or the control arm (n = 16). IL-8 was 
      not detectable. Exercise did not alter the maternal lipid profile. CONCLUSIONS: 
      The low level of physical activity achieved in obese women in the exercise 
      intervention arm was insufficient to alter gestational weight gain, MCP-1, leptin 
      or circulating lipid levels.
CI  - (c) 2015 The Royal Australian and New Zealand College of Obstetricians and 
      Gynaecologists.
FAU - Dekker Nitert, Marloes
AU  - Dekker Nitert M
AD  - School of Medicine, The University of Queensland, Herston, Queensland, Australia; 
      UQ Centre for Clinical Research, The University of Queensland, Herston, 
      Queensland, Australia.
FAU - Barrett, Helen L
AU  - Barrett HL
FAU - Denny, Kerina J
AU  - Denny KJ
FAU - McIntyre, H David
AU  - McIntyre HD
FAU - Callaway, Leonie K
AU  - Callaway LK
CN  - BAMBINO group
LA  - eng
PT  - Journal Article
PT  - Randomized Controlled Trial
PT  - Research Support, Non-U.S. Gov't
PL  - Australia
TA  - Aust N Z J Obstet Gynaecol
JT  - The Australian & New Zealand journal of obstetrics & gynaecology
JID - 0001027
RN  - 0 (CCL2 protein, human)
RN  - 0 (Chemokine CCL2)
RN  - 0 (Interleukin-8)
RN  - 0 (Leptin)
SB  - IM
MH  - Adult
MH  - Chemokine CCL2/blood
MH  - Exercise/*physiology
MH  - Female
MH  - Humans
MH  - Interleukin-8/blood
MH  - Leptin/blood
MH  - Obesity/*blood/therapy
MH  - Pilot Projects
MH  - Pregnancy
MH  - Pregnancy Complications/*blood/prevention & control
MH  - *Weight Gain
MH  - Young Adult
OTO - NOTNLM
OT  - exercise
OT  - gestational weight gain
OT  - lipids
OT  - obesity
OT  - pregnancy
FIR - Foxcroft, Katie
IR  - Foxcroft K
FIR - Lingwood, Barbara
IR  - Lingwood B
FIR - Colditz, Paul
IR  - Colditz P
FIR - Byrne, Nuala
IR  - Byrne N
FIR - Rowlands, Ingrid
IR  - Rowlands I
FIR - Groves, Ainsley
IR  - Groves A
FIR - Sansome, Xanthe
IR  - Sansome X
FIR - O'Connor, Briony
IR  - O'Connor B
FIR - Croaker, Susan
IR  - Croaker S
EDAT- 2015/02/18 06:00
MHDA- 2015/12/15 06:00
CRDT- 2015/02/18 06:00
PHST- 2014/08/31 00:00 [received]
PHST- 2014/11/11 00:00 [accepted]
PHST- 2015/02/18 06:00 [entrez]
PHST- 2015/02/18 06:00 [pubmed]
PHST- 2015/12/15 06:00 [medline]
AID - 10.1111/ajo.12300 [doi]
PST - ppublish
SO  - Aust N Z J Obstet Gynaecol. 2015 Feb;55(1):27-33. doi: 10.1111/ajo.12300.