PMID- 25690861
OWN - NLM
STAT- MEDLINE
DCOM- 20180815
LR  - 20200820
IS  - 1309-5730 (Electronic)
IS  - 1018-5615 (Print)
IS  - 1018-5615 (Linking)
VI  - 34
IP  - 1
DP  - 2018
TI  - Dedifferentiated Liposarcoma of the Gastroesophageal Junction.
PG  - 104-107
LID - 10.5146/tjpath.2014.01297 [doi]
AB  - Liposarcoma is one of the most common sarcomas in adults, but very rarely 
      presents as a primary in the upper gastrointestinal system. Herein, we present a 
      71-year-old male patient who underwent wedge excision biopsy twice and then fine 
      needle aspiration and total gastrectomy for a recurrent gastroeosophageal 
      junction mass. In microscopic sections, both well-differentiated and 
      dedifferentiated components were seen. Tumor cells were positive for MDM2, CDK4 
      and negative for CD117, DOG1, CD34, SMA, Desmin, S-100, HMB45, SOX10, AE1/AE3, 
      CAM5.2, CK18. Fluorescence in situ hybridization (FISH) was performed and MDM2 
      gene (12q15) amplification was detected. According to these findings, a diagnosis 
      of dedifferentiated liposarcoma was supported. We believe this is the first 
      reported case of dedifferentiated liposarcoma of the gastroesophageal junction.
FAU - Askan, Gokce
AU  - Askan G
AD  - Departments of Pathology, Marmara University Faculty of Medicine, ISTANBUL, 
      TURKEY.
FAU - Bagci, Pelin
AU  - Bagci P
FAU - Hameed, Meera
AU  - Hameed M
FAU - Basturk, Olca
AU  - Basturk O
LA  - eng
GR  - P30 CA008748/CA/NCI NIH HHS/United States
PT  - Case Reports
PT  - Journal Article
PL  - Turkey
TA  - Turk Patoloji Derg
JT  - Turk patoloji dergisi
JID - 9440471
SB  - IM
MH  - Aged
MH  - Esophagogastric Junction/*pathology
MH  - Humans
MH  - Liposarcoma/*pathology
MH  - Male
MH  - Stomach Neoplasms/*pathology
PMC - PMC7437155
MID - NIHMS1617791
EDAT- 2015/02/19 06:00
MHDA- 2018/08/16 06:00
PMCR- 2020/08/19
CRDT- 2015/02/19 06:00
PHST- 2015/02/19 06:00 [pubmed]
PHST- 2018/08/16 06:00 [medline]
PHST- 2015/02/19 06:00 [entrez]
PHST- 2020/08/19 00:00 [pmc-release]
AID - 10.5146/tjpath.2014.01297 [doi]
PST - ppublish
SO  - Turk Patoloji Derg. 2018;34(1):104-107. doi: 10.5146/tjpath.2014.01297.