PMID- 25692049
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20150218
LR  - 20201001
IS  - 2090-648X (Print)
IS  - 2090-6498 (Electronic)
IS  - 2090-6498 (Linking)
VI  - 2015
DP  - 2015
TI  - Profound hypoglycemia with ecstasy intoxication.
PG  - 483153
LID - 10.1155/2015/483153 [doi]
LID - 483153
AB  - Background. 3,4-Methylenedioxymethamphetamine (MDMA) or ecstasy is a synthetic 
      drug that is commonly abused for its stimulant and euphoric effects. Adverse MDMA 
      effects include hyperthermia, psychomotor agitation, hemodynamic compromise, 
      renal failure, hyponatremia, and coma. However, endogenous hyperinsulinemia with 
      severe persistent hypoglycemia has not been reported with MDMA use. Case Report. 
      We report the case of a 29-year-old woman who remained severely hypoglycemic 
      requiring continuous intravenous infusion of high-dose dextrose solutions for 
      more than 24 hours after MDMA intoxication. Serum insulin and C-peptide levels 
      confirmed marked endogenous hyperinsulinemia as the cause of the severe 
      hypoglycemia. Why Should an Emergency Physician Be Aware of This? Immediate and 
      frequent monitoring of blood glucose should be instituted in patients presenting 
      with MDMA ingestion particularly if found to be initially hypoglycemic. Early 
      recognition can help prevent the deleterious effects of untreated hypoglycemia 
      that can add to the morbidity from MDMA use. Clinicians need to be aware of this 
      side effect of MDMA so they can carefully monitor and treat it, especially in 
      patients presenting with altered mental status.
FAU - Carrera, Perliveh
AU  - Carrera P
AD  - Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN 
      55905, USA.
FAU - Iyer, Vivek N
AU  - Iyer VN
AD  - Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN 
      55905, USA.
LA  - eng
PT  - Journal Article
DEP - 20150127
PL  - United States
TA  - Case Rep Emerg Med
JT  - Case reports in emergency medicine
JID - 101591814
PMC - PMC4322300
EDAT- 2015/02/19 06:00
MHDA- 2015/02/19 06:01
PMCR- 2015/01/27
CRDT- 2015/02/19 06:00
PHST- 2014/10/08 00:00 [received]
PHST- 2015/01/10 00:00 [accepted]
PHST- 2015/02/19 06:00 [entrez]
PHST- 2015/02/19 06:00 [pubmed]
PHST- 2015/02/19 06:01 [medline]
PHST- 2015/01/27 00:00 [pmc-release]
AID - 10.1155/2015/483153 [doi]
PST - ppublish
SO  - Case Rep Emerg Med. 2015;2015:483153. doi: 10.1155/2015/483153. Epub 2015 Jan 27.