PMID- 25696027
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20201001
IS  - 1568-5888 (Print)
IS  - 1568-5888 (Linking)
VI  - 10
IP  - 1
DP  - 2002 Jan
TI  - Assessment of quality of life in patients with angina pectoris: Progress made by 
      the Dutch Mononitrate Quality-Of-Life (DUMQOL) Study Group.
PG  - 13-18
AB  - BACKGROUND: Two major issues in quality of life (QOL) research are the patient's 
      opinion as a contributing factor in QOL assessments, and the lack of sensitivity 
      of QOL assessments. OBJECTIVES: To review results from recent research by the 
      Dutch Mononitrate Quality Of Life (DUMQOL) Study Group relevant to these two 
      issues. METHODS: Using a test battery including Stewart's Short Form (SF)-36 
      Questionnaire and the DUMQOL-50 questionnaire, the DUMQOL Study Group tested the 
      hypothesis that the patient's opinion might be an independent determinant of QOL. 
      To do this, a stepwise multiple regression analysis of data from 82 patients 
      attending an outpatient clinic with stable angina pectoris was performed. 
      Secondly, using an odds ratio approach to QOL scores in 1350 outpatients with 
      stable angina pectoris who were attending a clinic, the DUMQOL Study Group 
      assessed the question whether relative scores might provide increased precision 
      in estimating the effects of patient characteristics on QOL data. RESULTS: 
      Psychological distress was the most important contributor to QOL (beta 0.43, 
      p<0.0001). Also, the patient's opinion on his/her QOL significantly contributed 
      to QOL (beta 0.22, p=0.032). Physical health status according to the patient's 
      judgement only made a borderline contribution (beta 0.19, p=0.71), while the 
      physician's judgement was not associated with QOL at all (beta 0.11, p=0.87). 
      Regarding the second issue, increased QOL difficulties were observed in New York 
      Heart Association (NYHA) angina class III-IV patients, in patients with 
      comorbidity, as well as in female and elderly patients. Odds ratios can be used 
      in these categories to predict the benefit from treatments. CONCLUSIONS: Recent 
      QOL research of the DUMQOL Study Group allows conclusions to be drawn that are 
      relevant to clinical practice. QOL should be defined in a subjective rather than 
      an objective method. The patient's opinion is an important independent 
      contributor to QOL. The comparison of absolute QOL scores lacks the sensitivity 
      to truly estimate QOL. The odds ratio approach of QOL scores provides increased 
      precision in estimating QOL.
FAU - Cleophas, T J
AU  - Cleophas TJ
FAU - Niemeyer, M G
AU  - Niemeyer MG
FAU - Zwinderman, A H
AU  - Zwinderman AH
FAU - Buunk, B
AU  - Buunk B
FAU - van der Wall, E E
AU  - van der Wall EE
LA  - eng
PT  - Journal Article
PL  - Netherlands
TA  - Neth Heart J
JT  - Netherlands heart journal : monthly journal of the Netherlands Society of 
      Cardiology and the Netherlands Heart Foundation
JID - 101095458
PMC - PMC2499672
OTO - NOTNLM
OT  - QOL
OT  - QOL assessments
OT  - angina pectoris
OT  - odds ratios
OT  - quality of life
EDAT- 2002/01/01 00:00
MHDA- 2002/01/01 00:01
PMCR- 2002/01/01
CRDT- 2015/02/20 06:00
PHST- 2015/02/20 06:00 [entrez]
PHST- 2002/01/01 00:00 [pubmed]
PHST- 2002/01/01 00:01 [medline]
PHST- 2002/01/01 00:00 [pmc-release]
PST - ppublish
SO  - Neth Heart J. 2002 Jan;10(1):13-18.