PMID- 25699223
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20210109
IS  - 2168-2372 (Print)
IS  - 2168-2372 (Electronic)
IS  - 2168-2372 (Linking)
VI  - 2
DP  - 2014
TI  - Quantitative Assessment of Single-Image Super-Resolution in Myocardial Scar 
      Imaging.
LID - 1800512 [pii]
AB  - Single-image super resolution is a process of obtaining a high-resolution image 
      from a set of low-resolution observations by signal processing. While super 
      resolution has been demonstrated to improve image quality in scaled down images 
      in the image domain, its effects on the Fourier-based image acquisition 
      technique, such as MRI, remains unknown.We performed high-resolution ex vivo late 
      gadolinium enhancement (LGE) magnetic resonance imaging (0.4 x 0.4 x 0.4 mm(3)) 
      in postinfarction swine hearts (n = 24). The swine hearts were divided into the 
      training set (n = 14) and the test set (n = 10), and in all hearts, 
      low-resolution images were simulated from the high-resolution images. In the 
      training set, super-resolution dictionaries with pairs of small matching patches 
      of the high- and low-resolution images were created. In the test set, super 
      resolution recovered high-resolution images from low-resolution images using the 
      dictionaries. The same algorithm was also applied to patient LGE (n = 4) to 
      assess its effects. Compared with interpolated images, super resolution 
      significantly improved basic image quality indices (P < 0.001). Super resolution 
      using Fourier-based zero padding achieved the best image quality. However, the 
      magnitude of improvement was small in images with zero padding. Super resolution 
      substantially improved the spatial resolution of the patient LGE images by 
      sharpening the edges of the heart and the scar. In conclusion, single-image super 
      resolution significantly improves image errors. However, the magnitude of 
      improvement was relatively small in images with Fourier-based zero padding. These 
      findings provide evidence to support its potential use in myocardial scar 
      imaging.
FAU - Ashikaga, Hiroshi
AU  - Ashikaga H
AD  - Division of Cardiology, The Johns Hopkins University School of Medicine, 
      Baltimore, MD 21287, USA ; Department of Biomedical Engineering, The Johns 
      Hopkins University School of Medicine, Baltimore, MD 21287, USA.
FAU - Estner, Heidi L
AU  - Estner HL
AD  - Deutsches Herzzentrum Munchen and Medizinische Klinik, Technische Universitat 
      Munchen, Munchen 85748, Germany.
FAU - Herzka, Daniel A
AU  - Herzka DA
AD  - Department of Biomedical Engineering, The Johns Hopkins University School of 
      Medicine, Baltimore, MD 21287, USA.
FAU - Mcveigh, Elliot R
AU  - Mcveigh ER
AD  - Division of Cardiology, The Johns Hopkins University School of Medicine, 
      Baltimore, MD 21287, USA.
FAU - Halperin, Henry R
AU  - Halperin HR
AD  - Division of Cardiology, The Johns Hopkins University School of Medicine, 
      Baltimore, MD 21287, USA ; Department of Biomedical Engineering, The Johns 
      Hopkins University School of Medicine, Baltimore, MD 21287, USA ; The Russell H. 
      Morgan Department of Radiology and Radiological Sciences, Johns Hopkins 
      University School of Medicine, Baltimore, MD.
LA  - eng
GR  - R01 HL064795/HL/NHLBI NIH HHS/United States
GR  - R01 HL094610/HL/NHLBI NIH HHS/United States
GR  - Z01 HL004609/ImNIH/Intramural NIH HHS/United States
GR  - Z01 HL004609-04/ImNIH/Intramural NIH HHS/United States
PT  - Journal Article
PL  - United States
TA  - IEEE J Transl Eng Health Med
JT  - IEEE journal of translational engineering in health and medicine
JID - 101623153
PMC - PMC4331080
MID - NIHMS658837
OTO - NOTNLM
OT  - Image processing
OT  - image quality
OT  - magnetic resonance imaging
OT  - myocardial scar
EDAT- 2015/02/24 06:00
MHDA- 2015/02/24 06:01
PMCR- 2014/01/30
CRDT- 2015/02/21 06:00
PHST- 2015/02/21 06:00 [entrez]
PHST- 2015/02/24 06:00 [pubmed]
PHST- 2015/02/24 06:01 [medline]
PHST- 2014/01/30 00:00 [pmc-release]
AID - 1800512 [pii]
AID - 10.1109/JTEHM.2014.2303806 [doi]
PST - ppublish
SO  - IEEE J Transl Eng Health Med. 2014;2:1800512. doi: 10.1109/JTEHM.2014.2303806.