PMID- 25724224
OWN - NLM
STAT- MEDLINE
DCOM- 20151111
LR  - 20181202
IS  - 1873-4499 (Electronic)
IS  - 0899-7071 (Linking)
VI  - 39
IP  - 3
DP  - 2015 May-Jun
TI  - Low-intensity late gadolinium enhancement predominates in hypertrophic 
      cardiomyopathy.
PG  - 432-6
LID - S0899-7071(15)00002-9 [pii]
LID - 10.1016/j.clinimag.2015.01.001 [doi]
AB  - AIM: Assess the extent of low- versus high-intensity late gadolinium enhancement 
      (LGE) in hypertrophic cardiomyopathy (HCM). METHODS: Low- versus high-intensity 
      LGE indexed volumes in 19 HCM patients were compared to 23 myocardial infarction 
      (MI) patients. RESULTS: Total, low-, and high-intensity LGE volumes in HCM vs. MI 
      were 7.6ml/m(2), 4.7, and 2.4 vs. 11.2, 2.5, and 7.1, respectively. Total LGE 
      volume did not differ (P=.13), though low- and high-intensity did (P=.05, .004). 
      67% versus 26% of all LGE was low-intensity in HCM versus MI (P<.001). 
      CONCLUSIONS: LGE in HCM is predominantly low-intensity, so a low threshold may be 
      the most appropriate.
CI  - Copyright (c) 2015 Elsevier Inc. All rights reserved.
FAU - Naeger, David M
AU  - Naeger DM
AD  - Department of Radiology and Biomedical Imaging, University of California, San 
      Francisco, 505 Parnassus Ave., M-391, San Francisco, CA 94143-0628. Electronic 
      address: david.naeger@ucsf.edu.
FAU - Higgins, Charles
AU  - Higgins C
AD  - Department of Radiology and Biomedical Imaging, University of California, San 
      Francisco, 505 Parnassus Ave., M-391, San Francisco, CA 94143-0628.
FAU - De Marco, Teresa
AU  - De Marco T
AD  - Department of Medicine, Division of Cardiology, University of California, San 
      Francisco, 505 Parnassus Ave., M-391, San Francisco, CA 94143-0628.
FAU - Muzzarelli, Stefano
AU  - Muzzarelli S
AD  - Department of Radiology and Biomedical Imaging, University of California, San 
      Francisco, 505 Parnassus Ave., M-391, San Francisco, CA 94143-0628.
FAU - Ordovas, Karen G
AU  - Ordovas KG
AD  - Department of Radiology and Biomedical Imaging, University of California, San 
      Francisco, 505 Parnassus Ave., M-391, San Francisco, CA 94143-0628.
LA  - eng
PT  - Journal Article
DEP - 20150114
PL  - United States
TA  - Clin Imaging
JT  - Clinical imaging
JID - 8911831
RN  - 0 (Contrast Media)
RN  - AU0V1LM3JT (Gadolinium)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Cardiomyopathy, Hypertrophic/*diagnosis
MH  - *Contrast Media
MH  - Female
MH  - *Gadolinium
MH  - Humans
MH  - Image Enhancement/*methods
MH  - Image Processing, Computer-Assisted
MH  - Imaging, Three-Dimensional
MH  - *Magnetic Resonance Imaging
MH  - Male
MH  - Middle Aged
MH  - Myocardium/pathology
MH  - Risk Factors
MH  - Young Adult
OTO - NOTNLM
OT  - DCE
OT  - HCM
OT  - Hypertrophic cardiomyopathy
OT  - LGE
OT  - Late gadolinium enhancement
EDAT- 2015/03/01 06:00
MHDA- 2015/11/12 06:00
CRDT- 2015/03/01 06:00
PHST- 2014/10/03 00:00 [received]
PHST- 2014/12/17 00:00 [revised]
PHST- 2015/01/05 00:00 [accepted]
PHST- 2015/03/01 06:00 [entrez]
PHST- 2015/03/01 06:00 [pubmed]
PHST- 2015/11/12 06:00 [medline]
AID - S0899-7071(15)00002-9 [pii]
AID - 10.1016/j.clinimag.2015.01.001 [doi]
PST - ppublish
SO  - Clin Imaging. 2015 May-Jun;39(3):432-6. doi: 10.1016/j.clinimag.2015.01.001. Epub 
      2015 Jan 14.