PMID- 25725957
OWN - NLM
STAT- MEDLINE
DCOM- 20150520
LR  - 20181202
IS  - 1873-3778 (Electronic)
IS  - 0021-9673 (Linking)
VI  - 1388
DP  - 2015 Apr 3
TI  - In situ synthesis of homochiral metal-organic framework in capillary column for 
      capillary electrochromatography enantioseparation.
PG  - 207-16
LID - S0021-9673(15)00278-2 [pii]
LID - 10.1016/j.chroma.2015.02.034 [doi]
AB  - Homochiral metal-organic frameworks (MOFs) are promising as porous stationary 
      phase for open-tubular capillary electrochromatography (OT-CEC) enantioseparation 
      owing to their fine-tuned pore sizes and large surface areas. In this work, the 
      homochiral MOF AlaZnCl was successfully coated on the inner wall of fused silica 
      capillary by an in situ, layer-by-layer self-assembly approach at room 
      temperature. The results of scanning electron microscopy (SEM), X-ray diffraction 
      (XRD), streaming potential (SP) and Fourier-transform infrared spectroscopy 
      (FT-IR) indicated that the homochiral MOF AlaZnCl was successfully coated on the 
      capillary inner wall. To evaluate the performance of the homochiral MOF AlaZnCl 
      coated capillary column, the enantioseparation was carried out by using six amine 
      drugs and monoamine neurotransmitters as model analytes and excellent 
      enantioseparation efficiency was achieved. Run-to-run, day-to-day, and 
      column-to-column relative standard deviations (RSDs) were all less than 5%. 
      Moreover, the separation efficiency of the homochiral MOF AlaZnCl coated 
      capillary column did not decrease obviously over 100 runs.
CI  - Copyright (c) 2015 Elsevier B.V. All rights reserved.
FAU - Pan, Congjie
AU  - Pan C
AD  - State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 
      730000, China; Department of Chemistry, Lanzhou University, Lanzhou 730000, 
      China.
FAU - Wang, Weifeng
AU  - Wang W
AD  - State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 
      730000, China; Department of Chemistry, Lanzhou University, Lanzhou 730000, 
      China.
FAU - Zhang, Huige
AU  - Zhang H
AD  - State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 
      730000, China; Department of Chemistry, Lanzhou University, Lanzhou 730000, 
      China.
FAU - Xu, Laifang
AU  - Xu L
AD  - State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 
      730000, China; Department of Chemistry, Lanzhou University, Lanzhou 730000, 
      China.
FAU - Chen, Xingguo
AU  - Chen X
AD  - State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 
      730000, China; Department of Chemistry, Lanzhou University, Lanzhou 730000, 
      China; Key Laboratory of Nonferrous Metal Chemistry and Resources Utilization of 
      Gansu Province, Lanzhou 730000, China. Electronic address: chenxg@lzu.edu.cn.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20150216
PL  - Netherlands
TA  - J Chromatogr A
JT  - Journal of chromatography. A
JID - 9318488
RN  - 0 (Organometallic Compounds)
RN  - 7631-86-9 (Silicon Dioxide)
SB  - IM
MH  - Capillary Electrochromatography/*methods
MH  - Microscopy, Electron, Scanning/*methods
MH  - Organometallic Compounds/*chemical synthesis
MH  - Porosity
MH  - Silicon Dioxide/*chemistry
MH  - Spectroscopy, Fourier Transform Infrared/*methods
MH  - Stereoisomerism
MH  - X-Ray Diffraction/*methods
OTO - NOTNLM
OT  - Enantioseparation
OT  - Homochiral metal-organic framework
OT  - In situ synthesis
OT  - MOF AlaZnCl
OT  - Open tubular capillary electrochromatography
EDAT- 2015/03/03 06:00
MHDA- 2015/05/21 06:00
CRDT- 2015/03/02 06:00
PHST- 2014/11/28 00:00 [received]
PHST- 2015/02/07 00:00 [revised]
PHST- 2015/02/10 00:00 [accepted]
PHST- 2015/03/02 06:00 [entrez]
PHST- 2015/03/03 06:00 [pubmed]
PHST- 2015/05/21 06:00 [medline]
AID - S0021-9673(15)00278-2 [pii]
AID - 10.1016/j.chroma.2015.02.034 [doi]
PST - ppublish
SO  - J Chromatogr A. 2015 Apr 3;1388:207-16. doi: 10.1016/j.chroma.2015.02.034. Epub 
      2015 Feb 16.