PMID- 25729696
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20150302
LR  - 20201001
IS  - 2230-8210 (Print)
IS  - 2230-9500 (Electronic)
IS  - 2230-9500 (Linking)
VI  - 19
IP  - 2
DP  - 2015 Mar-Apr
TI  - Seroprevalence of hepatitis C infection in type 2 diabetes mellitus.
PG  - 296-9
LID - 10.4103/2230-8210.149325 [doi]
AB  - INTRODUCTION: Hepatitis C is an emerging disease with different studies showing 
      varying prevalence rates across India. In several studies, prevalence of 
      hepatitis C infection was found to be higher in diabetics than nondiabetics. 
      However, none has been reported from India. OBJECTIVES: The aim was to determine 
      the sero-prevalence of hepatitis C infection in type 2 diabetes mellitus (T2DM). 
      SETTINGS AND DESIGN: Cross-sectional study of all T2DM patients attending 
      endocrine clinic in Regional Institute of Medical Sciences, Imphal from October 
      2011 to September 2013. SUBJECTS AND METHODS: All T2DM patients included and 
      exclusion criteria are patients with other forms of diabetes, liver failure, 
      renal failure, malignancy or other chronic illness. Patient's age, sex, height, 
      weight, body mass index, history of risk factors, etc., collected and 
      investigated for blood glucose fasting and prandial levels, transaminases levels, 
      hepatitis C virus (HCV) screening, etc.. STATISTICAL ANALYSIS: Statistical 
      analysis was performed using Statistical Package for the Social Sciences version 
      20; appropriate test used where applicable. RESULTS: Out of the 192 T2DM patients 
      screened, prevalence rate of HCV sero-positivity is found to be 5.7% (11/192), 
      higher in males. History of jaundice in the past was the only significant history 
      among sero-positive patients. Transaminases levels are significantly higher in 
      sero-postive cases. They had higher fasting and postprandial blood glucose, 
      fasting glucose levels being significantly higher. CONCLUSION: Our study shows a 
      slightly higher prevalence of hepatitis C infection in type 2 diabetics.
FAU - Laloo, Demitrost
AU  - Laloo D
AD  - Department of Medicine, Regional Institute of Medical Sciences, Imphal, Manipur, 
      India.
FAU - Walke, Prashant
AU  - Walke P
AD  - Department of Medicine, Regional Institute of Medical Sciences, Imphal, Manipur, 
      India.
FAU - Bhimo, Thongam
AU  - Bhimo T
AD  - Department of Medicine, Regional Institute of Medical Sciences, Imphal, Manipur, 
      India.
FAU - Prasad, Lallan
AU  - Prasad L
AD  - Department of Medicine, Regional Institute of Medical Sciences, Imphal, Manipur, 
      India.
FAU - Ranabir, Salam
AU  - Ranabir S
AD  - Department of Medicine, Regional Institute of Medical Sciences, Imphal, Manipur, 
      India.
LA  - eng
PT  - Journal Article
PL  - India
TA  - Indian J Endocrinol Metab
JT  - Indian journal of endocrinology and metabolism
JID - 101555690
PMC - PMC4319274
OTO - NOTNLM
OT  - Alanine transaminases
OT  - aspartate transaminases
OT  - hepatitis C virus
OT  - type 2 diabetes mellitus
COIS- Conflict of Interest: None declared.
EDAT- 2015/03/03 06:00
MHDA- 2015/03/03 06:01
PMCR- 2015/03/01
CRDT- 2015/03/03 06:00
PHST- 2015/03/03 06:00 [entrez]
PHST- 2015/03/03 06:00 [pubmed]
PHST- 2015/03/03 06:01 [medline]
PHST- 2015/03/01 00:00 [pmc-release]
AID - IJEM-19-296 [pii]
AID - 10.4103/2230-8210.149325 [doi]
PST - ppublish
SO  - Indian J Endocrinol Metab. 2015 Mar-Apr;19(2):296-9. doi: 
      10.4103/2230-8210.149325.