PMID- 25731192
OWN - NLM
STAT- MEDLINE
DCOM- 20160106
LR  - 20181202
IS  - 1502-4725 (Electronic)
IS  - 0803-9488 (Linking)
VI  - 69
IP  - 6
DP  - 2015 Aug
TI  - Do ictal EEG characteristics predict treatment outcomes in schizophrenic patients 
      undergoing electroconvulsive therapy?
PG  - 466-71
LID - 10.3109/08039488.2014.1003403 [doi]
AB  - OBJECTIVE: The aim of this study is to investigate the relationship between 
      features of electroencephalography (EEG), including seizure time, energy 
      threshold level and post-ictal suppression time, and clinical variables, 
      including treatment outcomes and side-effects, among schizophrenia inpatients 
      undergoing electroconvulsive therapy (ECT). METHOD: This is a naturalistic 
      follow-up study on schizophrenia patients, diagnosed using DSM-IV-TR criteria, 
      treated by a psychosis inpatient service. All participants completed the Brief 
      Psychiatric Rating Scale (BPRS), the Global Assessment of Functioning (GAF) 
      scale, the Frontal Assessment Battery (FAB) and a Data Collection Form. 
      Assessments were made before treatment, during ECT and after treatment. FINDINGS: 
      Statistically significant improvements in both clinical and cognitive outcome 
      were noted after ECT in all patients. Predictors of improvement were sought by 
      evaluating electrophysiological variables measured at three time points (after 
      the third, fifth and seventh ECT sessions). Logistic regression analysis showed 
      that clinical outcome/improvement did not differ by seizure duration, threshold 
      energy level or post-ictal suppression time. DISCUSSION AND CONCLUSION: We found 
      that ictal EEG parameters measured at several ECT sessions did not predict 
      clinical recovery/outcomes. This may be because our centre defensively engages in 
      "very specific patient selection" when ECT is contemplated. ECT does not cause 
      short-term cognitive functional impairment and indeed improves cognition, because 
      symptoms of the schizophrenic episode are alleviated.
FAU - Simsek, Gulnihal Gokce
AU  - Simsek GG
AD  - Gulnihal Gokce Simsek, M.D., Psychiatry Department, Yozgat State Hospital , 
      Yozgat , Turkey.
FAU - Zincir, Selma
AU  - Zincir S
FAU - Gulec, Huseyin
AU  - Gulec H
FAU - Eksioglu, Sevgin
AU  - Eksioglu S
FAU - Semiz, Umit Basar
AU  - Semiz UB
FAU - Kurtulmus, Yasemin Sipka
AU  - Kurtulmus YS
LA  - eng
PT  - Clinical Study
PT  - Journal Article
DEP - 20150303
PL  - England
TA  - Nord J Psychiatry
JT  - Nordic journal of psychiatry
JID - 100927567
SB  - IM
MH  - Adult
MH  - Cognition Disorders/diagnosis/etiology
MH  - Electroconvulsive Therapy/adverse effects/*methods
MH  - *Electroencephalography
MH  - Evoked Potentials
MH  - Female
MH  - Follow-Up Studies
MH  - Humans
MH  - Male
MH  - Schizophrenia/*therapy
MH  - *Schizophrenic Psychology
MH  - Single-Blind Method
MH  - Treatment Outcome
OTO - NOTNLM
OT  - Electroconvulsive therapy
OT  - Ictal
OT  - Post-ictal suppression time
OT  - Schizophrenia
OT  - Side-effect
OT  - Treatment outcome
EDAT- 2015/03/04 06:00
MHDA- 2016/01/07 06:00
CRDT- 2015/03/04 06:00
PHST- 2015/03/04 06:00 [entrez]
PHST- 2015/03/04 06:00 [pubmed]
PHST- 2016/01/07 06:00 [medline]
AID - 10.3109/08039488.2014.1003403 [doi]
PST - ppublish
SO  - Nord J Psychiatry. 2015 Aug;69(6):466-71. doi: 10.3109/08039488.2014.1003403. 
      Epub 2015 Mar 3.