PMID- 25734937
OWN - NLM
STAT- MEDLINE
DCOM- 20160202
LR  - 20221207
IS  - 1557-8593 (Electronic)
IS  - 1520-9156 (Linking)
VI  - 17
IP  - 6
DP  - 2015 Jun
TI  - Electrical Myostimulation (EMS) Improves Glucose Metabolism and Oxygen Uptake in 
      Type 2 Diabetes Mellitus Patients--Results from the EMS Study.
PG  - 413-9
LID - 10.1089/dia.2014.0315 [doi]
AB  - AIMS: In patients with type 2 diabetes mellitus (T2DM) exercise training is 
      recommended to improve glycemic control. Electrical myostimulation (EMS) of 
      skeletal muscles is a new method to increase exercise capacity in patients with 
      chronic heart failure. The aim of this study was to investigate the effects of 
      EMS in T2DM on glucose metabolism, body composition, and exercise performance 
      using a newly designed stimulation suit that involves trunk, leg, and arm 
      muscles. SUBJECTS AND METHODS: Fifteen individuals (nine males; 61.7+/-14.8 years 
      old) were trained for 10 weeks twice weekly for 20 min with EMS. Effects on 
      glucose, glycosylated hemoglobin (HbA(1c)), oxygen consumption, and body 
      composition were evaluated. RESULTS: There was a significant increase of oxygen 
      uptake at the aerobic threshold from 12.3+/-0.8 to 13.3+/-0.7 mL/kg/min (P=0.003) and 
      of maximal work capacity from 96.9+/-6.4 to 101.4+/-7.9 W (P=0.046), with a 
      concomitant trend for improved maximal oxygen uptake (from 14.5+/-0.9 to 
      14.7+/-0.9 mL/kg/min [P=0.059]). Fasting blood glucose level decreased from 
      164.0+/-12.5 to 133.4+/-9.9 mg/dL (P=0.001), and HbA(1c) level decreased from 
      7.7+/-0.3% to 7.2+/-0.3% (P=0.041), whereas mean total weight (from 101.5+/-4.0 to 
      103.1+/-4.3 kg) and proportion of body fat (from 38.8+/-3.2% to 40.3+/-3.4%) remained 
      statistically unchanged. CONCLUSIONS: EMS can improve glucose metabolism and 
      functional performance in T2DM patients. These data suggest that EMS might emerge 
      as a novel additional therapeutic mode of exercise training and might help 
      patients to overcome their sedentary lifestyle.
FAU - van Buuren, Frank
AU  - van Buuren F
AD  - 1 Heart and Diabetes Center North Rhine-Westphalia, Department of Cardiology, 
      Ruhr University Bochum , Bad Oeynhausen, Germany .
FAU - Horstkotte, Dieter
AU  - Horstkotte D
FAU - Mellwig, Klaus Peter
AU  - Mellwig KP
FAU - Frund, Andreas
AU  - Frund A
FAU - Vlachojannis, Marios
AU  - Vlachojannis M
FAU - Bogunovic, Nicola
AU  - Bogunovic N
FAU - Dimitriadis, Zisis
AU  - Dimitriadis Z
FAU - Vortherms, Jurgen
AU  - Vortherms J
FAU - Humphrey, Reed
AU  - Humphrey R
FAU - Niebauer, Josef
AU  - Niebauer J
LA  - eng
PT  - Journal Article
DEP - 20150303
PL  - United States
TA  - Diabetes Technol Ther
JT  - Diabetes technology & therapeutics
JID - 100889084
RN  - 0 (Blood Glucose)
RN  - 0 (Glycated Hemoglobin A)
RN  - 0 (hemoglobin A1c protein, human)
SB  - IM
MH  - Adipose Tissue
MH  - Aged
MH  - Blood Glucose/*metabolism
MH  - Body Weight
MH  - Diabetes Mellitus, Type 2/blood/physiopathology/*therapy
MH  - Electric Stimulation Therapy/instrumentation/*methods
MH  - Exercise Therapy/instrumentation/methods
MH  - Fasting/blood
MH  - Female
MH  - Glycated Hemoglobin/metabolism
MH  - Humans
MH  - Longitudinal Studies
MH  - Male
MH  - Middle Aged
MH  - Muscle, Skeletal/*physiology
MH  - *Oxygen Consumption
MH  - Physical Exertion
MH  - Pilot Projects
EDAT- 2015/03/04 06:00
MHDA- 2016/02/03 06:00
CRDT- 2015/03/04 06:00
PHST- 2015/03/04 06:00 [entrez]
PHST- 2015/03/04 06:00 [pubmed]
PHST- 2016/02/03 06:00 [medline]
AID - 10.1089/dia.2014.0315 [doi]
PST - ppublish
SO  - Diabetes Technol Ther. 2015 Jun;17(6):413-9. doi: 10.1089/dia.2014.0315. Epub 
      2015 Mar 3.