PMID- 25735105
OWN - NLM
STAT- MEDLINE
DCOM- 20150604
LR  - 20181202
IS  - 2096-7993 (Print)
IS  - 2096-7993 (Linking)
VI  - 28
IP  - 21
DP  - 2014 Nov
TI  - [Relationship between the major histocompatibility complex class I chain-related 
      gene A expression and clinicopathologic features in laryngeal squamous 
      carcinoma].
PG  - 1694-696
AB  - OBJECTIVE: To investigate the expression of major histocompatibility complex 
      class I chain-related gene A (MICA) in laryngeal squamous cell carcinoma(LSCC), 
      and its clinical significance. METHOD: Immunohistochemistry and RT-PCR were used 
      to detect the expression of the MICA in LSCC and normal tissue samples. The 
      relationship between the expression of MICA and the clinicopathologic features 
      features were was analyzed. RESULT: Compared to the expression of MICA in normal 
      tissues samples, the expression of MICA in LSCC tissue was significantly 
      increased (P < 0.01). MICA expression level in carcinoma tissue was closely 
      related to the tumor-differentiation degree and TNM staging. CONCLUSION: Our 
      study suggests that MICA may play an important role in the invasion and 
      metastasis of LSCC, and could be a potential tumor maker for LSCC.
FAU - Jiang, Yan
AU  - Jiang Y
FAU - Wang, Pengju
AU  - Wang P
FAU - Yu, Ye
AU  - Yu Y
LA  - chi
PT  - Journal Article
PL  - China
TA  - Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
JT  - Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical 
      otorhinolaryngology, head, and neck surgery
JID - 101303164
RN  - 0 (Histocompatibility Antigens Class I)
RN  - 0 (MHC class I-related chain A)
SB  - IM
MH  - Aged
MH  - Carcinoma/*genetics/pathology
MH  - Female
MH  - Histocompatibility Antigens Class I/*genetics
MH  - Humans
MH  - Immunohistochemistry
MH  - Laryngeal Neoplasms/*genetics/pathology
MH  - Male
MH  - Middle Aged
MH  - Neoplasm Invasiveness
MH  - Neoplasm Staging
MH  - Real-Time Polymerase Chain Reaction
EDAT- 2015/03/05 06:00
MHDA- 2015/06/05 06:00
CRDT- 2015/03/05 06:00
PHST- 2015/03/05 06:00 [entrez]
PHST- 2015/03/05 06:00 [pubmed]
PHST- 2015/06/05 06:00 [medline]
PST - ppublish
SO  - Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2014 Nov;28(21):1694-696.