PMID- 25749019
OWN - NLM
STAT- MEDLINE
DCOM- 20160323
LR  - 20160526
IS  - 1573-2509 (Electronic)
IS  - 0920-9964 (Linking)
VI  - 164
IP  - 1-3
DP  - 2015 May
TI  - Social cognitive functioning in prodromal psychosis: A meta-analysis.
PG  - 28-34
LID - S0920-9964(15)00083-3 [pii]
LID - 10.1016/j.schres.2015.02.008 [doi]
AB  - BACKGROUND: There is substantial evidence regarding a social cognitive deficit in 
      schizophrenia, and it has been suggested to be a trait-marker of this disorder. 
      However, a domain-by-domain analysis of social cognitive deficits in individuals 
      at clinical high risk (CHR) for psychosis has not been performed. METHOD: 
      Electronic databases were searched for studies regarding social cognitive 
      performance in individuals at CHR. The included social cognitive domains, which 
      were classified based on the Social Cognition Psychometric Evaluation (SCOPE) 
      initiative of the National Institute of Mental Health (NIMH), were as follows: 
      theory of mind (ToM), social perception (SP), attributional bias (AB), and 
      emotion processing (EP). RESULTS: Twenty studies that included 1229 individuals 
      at CHR and 825 healthy controls met the inclusion criteria. The overall effect 
      size for social cognition was medium (g=-0.477). The largest effect size was 
      identified for AB (g=-0.708). A medium effect size was identified for EP 
      (g=-0.446) and ToM (g=-0.425), and small effects were identified for SP 
      (g=-0.383). CONCLUSION: This is the first quantitative domain-by-domain social 
      cognitive meta-analysis regarding CHR individuals. The present study indicated 
      that individuals at CHR exhibited significant impairments in all domains of 
      social cognition compared with healthy controls, with the largest effect size 
      identified for AB. The identification of social cognitive domains that reflect an 
      increased risk for impending psychosis and of predictors of the conversion to 
      psychosis via a longitudinal follow-up study is required.
CI  - Copyright (c) 2015 Elsevier B.V. All rights reserved.
FAU - Lee, Tae Young
AU  - Lee TY
AD  - Institute of Human Behavioral Medicine, Seoul National University-MRC, Seoul, 
      Republic of Korea; Department of Psychiatry, Seoul National University College of 
      Medicine, Seoul, Republic of Korea.
FAU - Hong, Sang Bin
AU  - Hong SB
AD  - Department of Psychiatry, Seoul National University College of Medicine, Seoul, 
      Republic of Korea.
FAU - Shin, Na Young
AU  - Shin NY
AD  - Institute of Human Behavioral Medicine, Seoul National University-MRC, Seoul, 
      Republic of Korea.
FAU - Kwon, Jun Soo
AU  - Kwon JS
AD  - Institute of Human Behavioral Medicine, Seoul National University-MRC, Seoul, 
      Republic of Korea; Department of Psychiatry, Seoul National University College of 
      Medicine, Seoul, Republic of Korea; Department of Brain & Cognitive Sciences, 
      Seoul National University College of Natural Sciences, Seoul, Republic of Korea. 
      Electronic address: kwonjs@snu.ac.kr.
LA  - eng
PT  - Journal Article
PT  - Meta-Analysis
PT  - Research Support, Non-U.S. Gov't
DEP - 20150304
PL  - Netherlands
TA  - Schizophr Res
JT  - Schizophrenia research
JID - 8804207
SB  - IM
MH  - Cognition Disorders/*etiology
MH  - Databases, Factual/statistics & numerical data
MH  - Humans
MH  - Neuropsychological Tests
MH  - *Prodromal Symptoms
MH  - Psychiatric Status Rating Scales
MH  - Psychotic Disorders/*complications/*psychology
MH  - Risk Factors
MH  - *Social Behavior
MH  - Theory of Mind
OTO - NOTNLM
OT  - Attribution bias
OT  - Clinical high risk for psychosis
OT  - Meta-analysis
OT  - Prodromal psychosis
OT  - Social cognition
EDAT- 2015/03/10 06:00
MHDA- 2016/03/24 06:00
CRDT- 2015/03/10 06:00
PHST- 2014/07/16 00:00 [received]
PHST- 2015/02/07 00:00 [revised]
PHST- 2015/02/07 00:00 [accepted]
PHST- 2015/03/10 06:00 [entrez]
PHST- 2015/03/10 06:00 [pubmed]
PHST- 2016/03/24 06:00 [medline]
AID - S0920-9964(15)00083-3 [pii]
AID - 10.1016/j.schres.2015.02.008 [doi]
PST - ppublish
SO  - Schizophr Res. 2015 May;164(1-3):28-34. doi: 10.1016/j.schres.2015.02.008. Epub 
      2015 Mar 4.