PMID- 25765969 OWN - NLM STAT- MEDLINE DCOM- 20160212 LR - 20150929 IS - 1551-3793 (Electronic) IS - 1551-3777 (Linking) VI - 11 IP - 4 DP - 2015 Oct TI - A review of the global pesticide legislation and the scale of challenge in reaching the global harmonization of food safety standards. PG - 525-36 LID - 10.1002/ieam.1635 [doi] AB - Pesticide use is important in agriculture to protect crops and improve productivity. However, pesticides have the potential to cause adverse human health or environmental effects, depending on exposure levels. This review examines existing pesticide legislation worldwide, focusing on the level of harmonization and impacts of differing legislation on food safety and trade. Pesticide legislation varies greatly worldwide, because countries have different requirements, guidelines, and legal limits for plant protection. Developed nations have more stringent regulations than developing countries, which lack the resources and expertise to adequately implement and enforce legislation. Global differences in pesticide legislation act as a technical barrier to trade. International parties such as the European Union (EU), Codex Alimentarius Commission (Codex), and North American Free Trade Agreement (NAFTA) have attempted to harmonize pesticide legislation by providing maximum residue limits (MRLs), but globally these limits remain variable. Globally harmonized pesticide standards would serve to increase productivity, profits, and trade and also enhance the ability to protect public health and the environment. CI - (c) 2015 SETAC. FAU - Handford, Caroline E AU - Handford CE AD - Institute for Global Food Security, School of Biological Sciences, Queen's University, Belfast, Northern Ireland, United Kingdom. FAU - Elliott, Christopher T AU - Elliott CT AD - Institute for Global Food Security, School of Biological Sciences, Queen's University, Belfast, Northern Ireland, United Kingdom. FAU - Campbell, Katrina AU - Campbell K LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PT - Review DEP - 20150430 PL - United States TA - Integr Environ Assess Manag JT - Integrated environmental assessment and management JID - 101234521 RN - 0 (Pesticides) SB - IM MH - Environmental Exposure/legislation & jurisprudence/standards MH - *Environmental Policy MH - Food Contamination/*legislation & jurisprudence MH - *Food Safety MH - International Cooperation MH - Legislation, Food/*standards MH - Pesticides/*standards OTO - NOTNLM OT - Food safety OT - Global harmonization OT - Legislation OT - Maximum residue limits OT - Pesticides EDAT- 2015/03/15 06:00 MHDA- 2016/02/13 06:00 CRDT- 2015/03/14 06:00 PHST- 2014/10/20 00:00 [received] PHST- 2015/01/20 00:00 [revised] PHST- 2015/02/23 00:00 [accepted] PHST- 2015/03/14 06:00 [entrez] PHST- 2015/03/15 06:00 [pubmed] PHST- 2016/02/13 06:00 [medline] AID - 10.1002/ieam.1635 [doi] PST - ppublish SO - Integr Environ Assess Manag. 2015 Oct;11(4):525-36. doi: 10.1002/ieam.1635. Epub 2015 Apr 30.