PMID- 25766305 OWN - NLM STAT- MEDLINE DCOM- 20160221 LR - 20221207 IS - 1423-0151 (Electronic) IS - 1011-7571 (Print) IS - 1011-7571 (Linking) VI - 24 IP - 3 DP - 2015 TI - Predictive Risk Factors for Fear of Hypoglycemia and Anxiety-Related Emotional Disorders among Adolescents with Type 1 Diabetes. PG - 222-30 LID - 10.1159/000375306 [doi] AB - OBJECTIVE: To explore the fear of hypoglycemia (FOH) and anxiety-related emotional disorders and their risk factors among adolescents with type 1 diabetes mellitus (T1DM). SUBJECTS AND METHODS: A cross-sectional study was conducted among 187 adolescents (aged 13-18 years; 92 males, 95 females) with T1DM at the Diabetes Treatment Center, Prince Sultan Military Medical City, Riyadh, Saudi Arabia, from June 2013 to February 2014. The participants were interviewed using FOH and Screen for Child Anxiety-Related Disorders (SCARED) scales. RESULTS: Females had significantly higher scores on all FOH and SCARED subscales compared to males. The mean scores for many subscales of FOH and SCARED were higher in the older age group (16-18 years), in those under multiple-dose injection (MDI) treatment (compared with the insulin pump treatment), and in those with a longer duration of T1DM. Similarly, significant differences were observed in those with high frequencies of hypoglycemia, passing out, hypoglycemia while asleep and awake, and hypoglycemia in front of friends and at school. Regression analysis revealed that higher age, female gender, MDI treatment, longer duration of T1DM, higher frequencies of hypoglycemia, passing out, hypoglycemia while asleep and awake, and hypoglycemia in front of friends and at school were the risk factors associated with the majority of the FOH and SCARED subscales. The behavior of the FOH subscale correlated with all the subscales of SCARED except the subscale of generalized anxiety disorder. Similarly, the FOH subscale of worry significantly correlated with all the subscales of SCARED. CONCLUSION: The strongest determinants of higher risk for the majority of the FOH and SCARED subscales were higher age, female gender, MDI treatment, longer duration of T1DM, higher frequency of hypoglycemia, passing out due to hypoglycemia, hypoglycemia while asleep and awake, and hypoglycemia in front of friends and at school. FAU - Al Hayek, Ayman A AU - Al Hayek AA AD - Department of Endocrinology and Diabetes, Diabetes Treatment Center, Prince Sultan Military Medical City, Riyadh, Saudi Arabia. FAU - Robert, Asirvatham A AU - Robert AA FAU - Braham, Rim B AU - Braham RB FAU - Issa, Besher A AU - Issa BA FAU - Al Sabaan, Fahad S AU - Al Sabaan FS LA - eng PT - Journal Article DEP - 20150228 PL - Switzerland TA - Med Princ Pract JT - Medical principles and practice : international journal of the Kuwait University, Health Science Centre JID - 8901334 RN - 0 (Glycated Hemoglobin A) RN - 0 (Insulin) SB - IM MH - Adolescent MH - Age Factors MH - Anxiety Disorders/*psychology MH - Cross-Sectional Studies MH - Diabetes Mellitus, Type 1/*complications/drug therapy/*psychology MH - Drug Administration Schedule MH - Fear MH - Female MH - Glycated Hemoglobin MH - Humans MH - Hypoglycemia/*complications/*psychology MH - Insulin/therapeutic use MH - Male MH - Risk Factors MH - Saudi Arabia/epidemiology MH - Sex Factors PMC - PMC5588232 EDAT- 2015/03/15 06:00 MHDA- 2016/02/22 06:00 PMCR- 2015/02/28 CRDT- 2015/03/14 06:00 PHST- 2014/07/09 00:00 [received] PHST- 2015/01/19 00:00 [accepted] PHST- 2015/03/14 06:00 [entrez] PHST- 2015/03/15 06:00 [pubmed] PHST- 2016/02/22 06:00 [medline] PHST- 2015/02/28 00:00 [pmc-release] AID - 000375306 [pii] AID - mpp-0024-0222 [pii] AID - 10.1159/000375306 [doi] PST - ppublish SO - Med Princ Pract. 2015;24(3):222-30. doi: 10.1159/000375306. Epub 2015 Feb 28.