PMID- 25769264
OWN - NLM
STAT- MEDLINE
DCOM- 20170314
LR  - 20220408
IS  - 1879-176X (Electronic)
IS  - 0300-5712 (Linking)
VI  - 43
IP  - 5
DP  - 2015 May
TI  - Impact of periodontal status on oral health-related quality of life in patients 
      with and without type 2 diabetes.
PG  - 506-11
LID - S0300-5712(15)00058-5 [pii]
LID - 10.1016/j.jdent.2015.03.001 [doi]
AB  - OBJECTIVES: To investigate the impact of periodontal status on oral 
      health-related quality of life (OHRQoL) in patients with and without type 2 
      diabetes mellitus (T2DM). METHODS: 61 patients with T2DM and 74 non-diabetic 
      patients matched for age, gender and periodontal status (health, gingivitis, 
      chronic periodontitis) were recruited. The oral health impact profile (OHIP)-49 
      was self-completed by all participants at baseline and by the patients with 
      periodontitis at 3 months and 6 months after non-surgical periodontal therapy. 
      RESULTS: There were no significant differences in the overall OHIP-49 summary 
      scores between patients with T2DM (median; interquartile range; 37.0; 19.5-61.0) 
      and without T2DM (30.4; 16.8-51.0) (p>0.05). Among non-diabetic patients, there 
      were significantly higher OHIP-49 scores (indicating poorer OHRQoL) in patients 
      with gingivitis (41.0; 19.7-75.7) and periodontitis (33.0; 19.9-52.5) compared to 
      patients who were periodontally healthy (11.1; 7.1-34.5) (p<0.05), though such an 
      effect was not observed in the patients with diabetes. In the non-diabetic 
      patients with periodontitis, statistically significant reductions in OHIP-49 
      scores were noted in the psychological discomfort and psychological disability 
      domains following periodontal treatment, indicating an improvement in OHRQoL. In 
      contrast, there were no statistically significant changes in OHIP-49 scores 
      following periodontal treatment in the patients with diabetes. CONCLUSION: T2DM 
      does not impact on overall OHRQoL as measured by OHIP-49. Chronic periodontitis 
      and gingivitis were associated with poorer OHRQoL in non-diabetic patients, with 
      evidence of improvements following periodontal treatment, but no such effects 
      were observed in patients with diabetes. CLINICAL SIGNIFICANCE: Gingivitis and 
      periodontitis are associated with reduced OHRQoL compared to periodontal health 
      in non-diabetic patients, with improvements following treatment of periodontitis. 
      No impact of type 2 diabetes on OHRQoL was noted; this may be related to the 
      burden of chronic disease (diabetes) minimising the impact of oral health issues 
      on OHRQoL.
CI  - Copyright (c) 2015 Elsevier Ltd. All rights reserved.
FAU - Irani, F C
AU  - Irani FC
AD  - School of Dental Sciences and Centre for Oral Health Research, Newcastle 
      University, UK.
FAU - Wassall, R R
AU  - Wassall RR
AD  - School of Dental Sciences and Centre for Oral Health Research, Newcastle 
      University, UK.
FAU - Preshaw, P M
AU  - Preshaw PM
AD  - School of Dental Sciences and Centre for Oral Health Research, Newcastle 
      University, UK; Institute of Cellular Medicine, Newcastle University, UK. 
      Electronic address: philip.preshaw@newcastle.ac.uk.
LA  - eng
GR  - TRF-2014-07-012/DH_/Department of Health/United Kingdom
PT  - Journal Article
DEP - 20150310
PL  - England
TA  - J Dent
JT  - Journal of dentistry
JID - 0354422
SB  - IM
MH  - Adult
MH  - Case-Control Studies
MH  - Chronic Periodontitis/*physiopathology
MH  - Dental Care
MH  - Diabetes Mellitus, Type 2/*physiopathology
MH  - Female
MH  - Gingivitis/*physiopathology
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - *Oral Health
MH  - Periodontal Diseases/physiopathology
MH  - Periodontal Index
MH  - Quality of Life
MH  - Surveys and Questionnaires
MH  - United Kingdom
OTO - NOTNLM
OT  - Gingivitis
OT  - OHIP-49
OT  - OHRQoL
OT  - Oral health impact profile-49
OT  - Oral health-related quality of life
OT  - Periodontal diseases
OT  - Periodontitis
OT  - Type 2 diabetes mellitus
EDAT- 2015/03/15 06:00
MHDA- 2017/03/16 06:00
CRDT- 2015/03/15 06:00
PHST- 2015/02/20 00:00 [received]
PHST- 2015/03/02 00:00 [revised]
PHST- 2015/03/03 00:00 [accepted]
PHST- 2015/03/15 06:00 [entrez]
PHST- 2015/03/15 06:00 [pubmed]
PHST- 2017/03/16 06:00 [medline]
AID - S0300-5712(15)00058-5 [pii]
AID - 10.1016/j.jdent.2015.03.001 [doi]
PST - ppublish
SO  - J Dent. 2015 May;43(5):506-11. doi: 10.1016/j.jdent.2015.03.001. Epub 2015 Mar 
      10.