PMID- 25770679
OWN - NLM
STAT- MEDLINE
DCOM- 20160328
LR  - 20181202
IS  - 1477-2566 (Electronic)
IS  - 1465-3249 (Linking)
VI  - 17
IP  - 6
DP  - 2015 Jun
TI  - Immunogenetic factors in the selection of cord blood units for transplantation: 
      current search strategies and future perspectives.
PG  - 702-710
LID - S1465-3249(15)00086-9 [pii]
LID - 10.1016/j.jcyt.2015.03.002 [doi]
AB  - Hematopoietic stem cell transplantation is currently used as a curative treatment 
      for patients with malignant and non-malignant hematologic diseases. Human 
      leukocyte antigen (HLA) matching is a major determinant for hematopoietic stem 
      cell transplantation outcome. For patients lacking a fully HLA-matched donor, 
      umbilical cord blood (UCB) units are alternative sources of hematopoietic stem 
      cells because UCB transplantation allows a less stringent HLA matching. However, 
      selection of the optimal UCB units remains challenging. The current UCB donor 
      selection strategies are based on both cell dose and HLA matching. This Review 
      focuses on the immunogenetic factors that influence UCB donor selection and 
      highlights the future perspectives in UCB donor search.
CI  - Copyright (c) 2015 International Society for Cellular Therapy. Published by 
      Elsevier Inc. All rights reserved.
FAU - Geneugelijk, Kirsten
AU  - Geneugelijk K
AD  - Laboratory of Translational Immunology, UMC Utrecht, Utrecht, The Netherlands.
FAU - Spierings, Eric
AU  - Spierings E
AD  - Laboratory of Translational Immunology, UMC Utrecht, Utrecht, The Netherlands. 
      Electronic address: e.spierings@umcutrecht.nl.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20150312
PL  - England
TA  - Cytotherapy
JT  - Cytotherapy
JID - 100895309
RN  - 0 (HLA Antigens)
SB  - IM
MH  - *Cord Blood Stem Cell Transplantation
MH  - Fetal Blood/cytology/*immunology
MH  - HLA Antigens/immunology
MH  - Histocompatibility Testing
MH  - Humans
MH  - *Immunogenetics
MH  - Inheritance Patterns
OTO - NOTNLM
OT  - HLA
OT  - PIRCHE
OT  - cord blood transplantation
OT  - donor search
EDAT- 2015/03/17 06:00
MHDA- 2016/03/29 06:00
CRDT- 2015/03/16 06:00
PHST- 2015/02/23 00:00 [received]
PHST- 2015/02/24 00:00 [accepted]
PHST- 2015/03/16 06:00 [entrez]
PHST- 2015/03/17 06:00 [pubmed]
PHST- 2016/03/29 06:00 [medline]
AID - S1465-3249(15)00086-9 [pii]
AID - 10.1016/j.jcyt.2015.03.002 [doi]
PST - ppublish
SO  - Cytotherapy. 2015 Jun;17(6):702-710. doi: 10.1016/j.jcyt.2015.03.002. Epub 2015 
      Mar 12.