PMID- 25772155 OWN - NLM STAT- MEDLINE DCOM- 20161017 LR - 20181113 IS - 1522-2594 (Electronic) IS - 0740-3194 (Print) IS - 0740-3194 (Linking) VI - 75 IP - 2 DP - 2016 Feb TI - Modified wideband three-dimensional late gadolinium enhancement MRI for patients with implantable cardiac devices. PG - 572-84 LID - 10.1002/mrm.25601 [doi] AB - PURPOSE: To study the effects of cardiac devices on three-dimensional (3D) late gadolinium enhancement (LGE) MRI and to develop a 3D LGE protocol for implantable cardioverter defibrillator (ICD) patients with reduced image artifacts. THEORY AND METHODS: The 3D LGE sequence was modified by implementing a wideband inversion pulse, which reduces hyperintensity artifacts, and by increasing bandwidth of the excitation pulse. The modified wideband 3D LGE sequence was tested in phantoms and evaluated in six volunteers and five patients with ICDs. RESULTS: Phantom and in vivo studies results demonstrated extended signal void and ripple artifacts in 3D LGE that were associated with ICDs. The reason for these artifacts was slab profile distortion and the subsequent aliasing in the slice-encoding direction. The modified wideband 3D LGE provided significantly reduced ripple artifacts than 3D LGE with wideband inversion only. Comparison of 3D and 2D LGE images demonstrated improved spatial resolution of the heart using 3D LGE. CONCLUSION: Increased bandwidth of the inversion and excitation pulses can significantly reduce image artifacts associated with ICDs. Our modified wideband 3D LGE protocol can be readily used for imaging patients with ICDs given appropriate safety guidelines are followed. CI - (c) 2015 Wiley Periodicals, Inc. FAU - Rashid, Shams AU - Rashid S AD - Department of Radiological Sciences, David Geffen School of Medicine, University of California, Los Angeles, California, USA. FAU - Rapacchi, Stanislas AU - Rapacchi S AD - Department of Radiological Sciences, David Geffen School of Medicine, University of California, Los Angeles, California, USA. FAU - Shivkumar, Kalyanam AU - Shivkumar K AD - Department of Radiological Sciences, David Geffen School of Medicine, University of California, Los Angeles, California, USA. AD - UCLA Cardiac Arrhythmia Center, David Geffen School of Medicine, University of California, Los Angeles, California, USA. FAU - Plotnik, Adam AU - Plotnik A AD - Department of Radiological Sciences, David Geffen School of Medicine, University of California, Los Angeles, California, USA. FAU - Finn, J Paul AU - Finn JP AD - Department of Radiological Sciences, David Geffen School of Medicine, University of California, Los Angeles, California, USA. AD - Biomedical Physics Inter-Departmental Graduate Program, University of California, Los Angeles, California, USA. FAU - Hu, Peng AU - Hu P AD - Department of Radiological Sciences, David Geffen School of Medicine, University of California, Los Angeles, California, USA. AD - Biomedical Physics Inter-Departmental Graduate Program, University of California, Los Angeles, California, USA. LA - eng GR - R01 HL084261/HL/NHLBI NIH HHS/United States GR - R21 HL118533/HL/NHLBI NIH HHS/United States GR - 1R21HL118533/HL/NHLBI NIH HHS/United States PT - Journal Article PT - Research Support, N.I.H., Extramural DEP - 20150313 PL - United States TA - Magn Reson Med JT - Magnetic resonance in medicine JID - 8505245 RN - 0 (Contrast Media) RN - K2I13DR72L (Gadolinium DTPA) SB - IM MH - Artifacts MH - Contrast Media MH - *Defibrillators, Implantable MH - Gadolinium DTPA MH - Humans MH - Image Enhancement/methods MH - Imaging, Three-Dimensional/methods MH - Magnetic Resonance Imaging/*methods MH - Phantoms, Imaging MH - Signal-To-Noise Ratio PMC - PMC4661130 MID - NIHMS738375 OTO - NOTNLM OT - Three dimensional late gadolinium enhancement OT - delayed enhancement OT - hyperintensity artifact OT - implantable cardiac devices OT - implantable cardioverter defibrillator OT - metal artifact reduction OT - wideband inversion EDAT- 2015/03/17 06:00 MHDA- 2016/10/19 06:00 PMCR- 2016/02/01 CRDT- 2015/03/17 06:00 PHST- 2014/05/15 00:00 [received] PHST- 2014/12/11 00:00 [revised] PHST- 2014/12/13 00:00 [accepted] PHST- 2015/03/17 06:00 [entrez] PHST- 2015/03/17 06:00 [pubmed] PHST- 2016/10/19 06:00 [medline] PHST- 2016/02/01 00:00 [pmc-release] AID - 10.1002/mrm.25601 [doi] PST - ppublish SO - Magn Reson Med. 2016 Feb;75(2):572-84. doi: 10.1002/mrm.25601. Epub 2015 Mar 13.