PMID- 25772561
OWN - NLM
STAT- MEDLINE
DCOM- 20160107
LR  - 20191210
IS  - 1618-2650 (Electronic)
IS  - 1618-2642 (Linking)
VI  - 407
IP  - 13
DP  - 2015 May
TI  - Exploring matrix effects in liquid chromatography-tandem mass spectrometry 
      determination of pesticide residues in tropical fruits.
PG  - 3667-81
LID - 10.1007/s00216-015-8586-5 [doi]
AB  - Tropical fruits are being increasingly consumed around the world because of their 
      appreciated characteristics, particularly their high nutritional value and 
      distinctive taste, which are different from those of traditional fruits. Owing to 
      their introduction into international markets it is necessary to have a reliable 
      analytical methodology available for the sensitive determination of pesticide 
      residues in order to monitor the compliance of maximum residue limits (MRLs). 
      From an analytical point of view, tropical fruits have generally been far less 
      studied than other fruits frequently consumed in the European Union or USA, which 
      are among the most important markets. In this work, LC-MS/MS-based methodology 
      using a triple quadrupole analyzer was developed for the multi-residue 
      determination of selected pesticides and metabolites in tropical fruits, which 
      were selected among the most popular in Colombia, one of the most important 
      suppliers of tropical fruits around the world. After selection of a QuEChERS 
      (Quick, Easy, Cheap, Effective, Rugged, and Safe)-based sample treatment, the 
      study focused on the evaluation of matrix effects, in order to find a simple way 
      for their correction. Twelve different food matrices were selected to perform 
      this study: the seven Colombian tropical fruits of highest value for domestic and 
      international markets (uchuva, tamarillo, granadilla, gulupa, maracuya, papaya, 
      and pithaya), and five more matrices highly consumed in Colombia (lulo, 
      carambolo, feijoa, mangostan, and guayaba). Twenty compounds, including 
      pesticides widely applied in tropical fruits pest control and several metabolites 
      considered in residue definition, were used as model compounds in this work. 
      Correction factors were used on the basis of calibration graphs obtained with 
      standards in solvent and in matrix, and their usefulness was supported by 
      validation of the method in all the matrices tested at 0.01 and 0.1 mg/kg. The 
      analysis of real-world samples revealed the presence of several target compounds 
      that were identified by the acquisition of two MS/MS transitions, and by ion 
      intensity ratio and retention time agreement.
FAU - Botero-Coy, Ana Maria
AU  - Botero-Coy AM
AD  - Research Institute for Pesticides and Water, University Jaume I, 12071, 
      Castellon, Spain.
FAU - Marin, Jose M
AU  - Marin JM
FAU - Serrano, Roque
AU  - Serrano R
FAU - Sancho, Juan Vicente
AU  - Sancho JV
FAU - Hernandez, Felix
AU  - Hernandez F
LA  - eng
PT  - Comparative Study
PT  - Evaluation Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20150314
PL  - Germany
TA  - Anal Bioanal Chem
JT  - Analytical and bioanalytical chemistry
JID - 101134327
RN  - 0 (Pesticide Residues)
SB  - IM
MH  - Chromatography, Liquid/*methods
MH  - Colombia
MH  - Food Analysis/*methods
MH  - Food Contamination/*analysis
MH  - Fruit/*chemistry
MH  - Pesticide Residues/*analysis
MH  - Reproducibility of Results
MH  - Sensitivity and Specificity
MH  - Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization/*methods
MH  - Tropical Climate
EDAT- 2015/03/17 06:00
MHDA- 2016/01/08 06:00
CRDT- 2015/03/17 06:00
PHST- 2014/11/27 00:00 [received]
PHST- 2015/02/20 00:00 [accepted]
PHST- 2015/02/10 00:00 [revised]
PHST- 2015/03/17 06:00 [entrez]
PHST- 2015/03/17 06:00 [pubmed]
PHST- 2016/01/08 06:00 [medline]
AID - 10.1007/s00216-015-8586-5 [doi]
PST - ppublish
SO  - Anal Bioanal Chem. 2015 May;407(13):3667-81. doi: 10.1007/s00216-015-8586-5. Epub 
      2015 Mar 14.