PMID- 25784498 OWN - NLM STAT- MEDLINE DCOM- 20160720 LR - 20151010 IS - 1753-9455 (Electronic) IS - 1753-9447 (Linking) VI - 9 IP - 5 DP - 2015 Oct TI - The relationship of TIMI risk index with SYNTAX and Gensini risk scores in predicting the extent and severity of coronary artery disease in patients with STEMI undergoing primary percutaneous coronary intervention. PG - 257-66 LID - 10.1177/1753944715574814 [doi] AB - OBJECTIVE: The prognostic value of the Global Registry of Acute Coronary Events (GRACE) risk score (GRS) and the Thrombolysis in Myocardial Infarction (TIMI) risk index (TRI) have been reported in patients with coronary artery disease (CAD). In this study, we sought to evaluate the association between TRI and the extent and severity of CAD evaluated by SYNTAX score (SS) and Gensini score in patients with ST elevation myocardial infarction (STEMI). METHODS: A total of 290 patients with STEMI were included in the study. GRS and TRI were calculated on admission using specified variables. The extent and severity of CAD were evaluated using the SS and Gensini scores. The patients were divided into low (TRI ⩽19), intermediate (TRI 19-30), and high (TRI ⩾30) risk groups. A Pearson correlation analysis was used for the relationship between TRI, GRS, Gensini score and SS. RESULTS: There were significant differences in the mean age (p < 0.001), admission heart rate (p < 0.001), admission systolic blood pressure (p = 0.009), SS (p < 0.001), GRS (p < 0.001) and in-hospital major adverse cardiac events (MACE) in all patients between the low, intermediate and high TRI risk groups. There was a positive significant correlation between TRI and SS (r = 0.24, p < 0.001), Gensini score (r = 0.18, p = 0.002), GRS (r = 0.74, p = 0.001) and in-hospital MACE (r = 0.29, p < 0.001). CONCLUSION: TRI is significantly related to SS and Gensini score in predicting the extent and severity of CAD in patients with STEMI. CI - (c) The Author(s), 2015. FAU - Acet, Halit AU - Acet H AD - Faculty of Medicine, Department of Cardiology, Dicle Universty, Diyarbakir 21280, Turkey halitacet@gmail.com. FAU - Ertas, Faruk AU - Ertas F AD - Faculty of Medicine, Department of Cardiology, Dicle Universty, Diyarbakir, Turkey. FAU - Bilik, Mehmet Zihni AU - Bilik MZ AD - Faculty of Medicine, Department of Cardiology, Dicle Universty, Diyarbakir, Turkey. FAU - Aydin, Mesut AU - Aydin M AD - Faculty of Medicine, Department of Cardiology, Dicle Universty, Diyarbakir, Turkey. FAU - Yuksel, Murat AU - Yuksel M AD - Faculty of Medicine, Department of Cardiology, Dicle Universty, Diyarbakir, Turkey. FAU - Polat, Nihat AU - Polat N AD - Faculty of Medicine, Department of Cardiology, Dicle Universty, Diyarbakir, Turkey. FAU - Yildiz, Abdulkadir AU - Yildiz A AD - Faculty of Medicine, Department of Cardiology, Dicle Universty, Diyarbakir, Turkey. FAU - Ozyurtlu, Ferhat AU - Ozyurtlu F AD - Faculty of Medicine, Department of Cardiology, Izmir Universty, Izmir, Turkey. FAU - Akil, Mehmet Ata AU - Akil MA AD - Faculty of Medicine, Department of Cardiology, Dicle Universty, Diyarbakir, Turkey. FAU - Ciftci, Leyla AU - Ciftci L AD - Faculty of Medicine, Department of Cardiology, Dicle Universty, Diyarbakir, Turkey. FAU - Ozbek, Mehmet AU - Ozbek M AD - Faculty of Medicine, Department of Cardiology, Dicle Universty, Diyarbakir, Turkey. FAU - Alan, Sait AU - Alan S AD - Faculty of Medicine, Department of Cardiology, Dicle Universty, Diyarbakir, Turkey. FAU - Toprak, Nizamettin AU - Toprak N AD - Faculty of Medicine, Department of Cardiology, Dicle Universty, Diyarbakir, Turkey. LA - eng PT - Journal Article DEP - 20150316 PL - England TA - Ther Adv Cardiovasc Dis JT - Therapeutic advances in cardiovascular disease JID - 101316343 SB - IM MH - Adult MH - Aged MH - Aged, 80 and over MH - Blood Pressure/physiology MH - Coronary Artery Disease/*physiopathology MH - Female MH - Heart Rate/physiology MH - Humans MH - Male MH - Middle Aged MH - Myocardial Infarction/*physiopathology MH - *Percutaneous Coronary Intervention MH - Prognosis MH - Retrospective Studies MH - Risk Assessment/methods MH - Severity of Illness Index OTO - NOTNLM OT - GRACE risk score OT - Gensini score OT - STEMI OT - SYNTAX score OT - TIMI risk index OT - TIMI risk score EDAT- 2015/03/19 06:00 MHDA- 2016/07/21 06:00 CRDT- 2015/03/19 06:00 PHST- 2015/03/19 06:00 [entrez] PHST- 2015/03/19 06:00 [pubmed] PHST- 2016/07/21 06:00 [medline] AID - 1753944715574814 [pii] AID - 10.1177/1753944715574814 [doi] PST - ppublish SO - Ther Adv Cardiovasc Dis. 2015 Oct;9(5):257-66. doi: 10.1177/1753944715574814. Epub 2015 Mar 16.