PMID- 25787911
OWN - NLM
STAT- MEDLINE
DCOM- 20151222
LR  - 20150319
IS  - 1881-7823 (Electronic)
IS  - 1881-7815 (Linking)
VI  - 9
IP  - 1
DP  - 2015 Feb
TI  - Short- and long-term outcomes of hepatectomy with or without 
      radiofrequency-assist for the treatment of hepatocellular carcinomas: a 
      retrospective comparative cohort study.
PG  - 65-72
LID - 10.5582/bst.2014.01142 [doi]
AB  - The objective of this study was to compare the short- and long-term outcomes of 
      radiofrequency-assisted liver resection (RFLR) and conventional clamp-crushing 
      liver resection (CCLR) and to evaluate the safety and efficiency of RFLR. Between 
      January 2008 and December 2012, a total of 597 patients with hepatocellular 
      carcinoma (HCC) who underwent curative hepatectomy were identified. A total of 
      272 patients underwent RFLR, and 325 patients received CCLR. The short- and 
      long-term outcomes were compared. The patients in the RFLR and CCLR groups showed 
      similar baseline characteristics. The RFLR group showed less intraoperative blood 
      loss (485.5 vs. 763.2 mL, p = 0.003), a lower transfusion requirement rate (19.1 
      vs. 31.7%, p </= 0.01), shorter surgery duration (211 vs. 296 min, p </= 0.01) and a 
      lower vascular inflow occlusion rate (25.7 vs. 33.8%, p = 0.032). No significant 
      postoperative changes in bilirubin or liver enzymes were observed in the two 
      groups. The degree of postoperative complications and morbidity did not 
      significantly differ between the two groups. There were no significant 
      differences in the 1-, 2- and 3-year overall survival rates (73.8%, 58.5%, and 
      55.7% vs. 80.8%, 65.8%, and 56.2%, respectively) or disease-free rates (51.9%, 
      47.2%, and 46.0% vs. 54.5%, 44.9%, and 38.5%, respectively) between the RFLR and 
      CCLR groups. These results suggested RFLR was a safe and efficient method for 
      patients with HCC. RFLR was associated with decreased blood loss, fewer blood 
      transfusions, shorter surgery times and less vascular inflow occlusion 
      application. The RFLR group did not show increased liver injury or postoperative 
      morbidity or mortality.
FAU - Guo, Rui
AU  - Guo R
AD  - Institute of Hepatobiliary Surgery, Southwest Hospital, Third Military Medical 
      University.
FAU - Feng, Xiaobin
AU  - Feng X
FAU - Xiao, Senlin
AU  - Xiao S
FAU - Yan, Jun
AU  - Yan J
FAU - Xia, Feng
AU  - Xia F
FAU - Ma, Kuansheng
AU  - Ma K
FAU - Li, Xiaowu
AU  - Li X
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Japan
TA  - Biosci Trends
JT  - Bioscience trends
JID - 101502754
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Carcinoma, Hepatocellular/*surgery
MH  - Catheter Ablation/*methods
MH  - Cohort Studies
MH  - Disease-Free Survival
MH  - Female
MH  - Hepatectomy/*methods
MH  - Humans
MH  - Liver Neoplasms/*surgery
MH  - Male
MH  - Middle Aged
MH  - Retrospective Studies
MH  - Treatment Outcome
MH  - Young Adult
EDAT- 2015/03/20 06:00
MHDA- 2015/12/23 06:00
CRDT- 2015/03/20 06:00
PHST- 2015/03/20 06:00 [entrez]
PHST- 2015/03/20 06:00 [pubmed]
PHST- 2015/12/23 06:00 [medline]
AID - 10.5582/bst.2014.01142 [doi]
PST - ppublish
SO  - Biosci Trends. 2015 Feb;9(1):65-72. doi: 10.5582/bst.2014.01142.