PMID- 25791144 OWN - NLM STAT- MEDLINE DCOM- 20161215 LR - 20181202 IS - 1527-5418 (Electronic) IS - 0890-8567 (Linking) VI - 54 IP - 4 DP - 2015 Apr TI - Group therapy for adolescents with attention-deficit/hyperactivity disorder: a randomized controlled trial. PG - 275-82 LID - S0890-8567(15)00036-2 [pii] LID - 10.1016/j.jaac.2014.12.016 [doi] AB - OBJECTIVE: To determine the efficacy of group cognitive-behavioral therapy (CBT) on adolescents with attention-deficit/hyperactivity disorder (ADHD) who were in pharmacological treatment but still had persistent symptoms. METHOD: We conducted a multicenter, randomized, rater-blinded, controlled trial between April 2012 and May 2014 in a cohort of 119 adolescents (15-21 years of age). Participants were randomly assigned to 12 manualized group CBT sessions (n = 45) or a waiting list control group (n = 44). Primary outcomes were assessed by a blinded evaluator (ADHD Rating Scale [ADHD-RS], Clinical Global Impression Scale for Severity [CGI-S], Global Assessment of Functioning [GAF]) before and after treatment, as well as by self-report and parent informant ratings. RESULTS: Of the initial 119 participants enrolled, 89 completed treatment. A mixed-effects model analysis revealed that participants who were assigned to the group CBT sessions experienced significantly reduced ADHD symptoms compared to the control group (ADHD-RS Adolescent: -7.46, 95% CI = -9.56 to -5.36, p < .001, d = 7.5; ADHD-RS Parents: -9.11, 95% CI = -11.48 to -6.75, p < .001, d = 8.38; CGI-S Self-Report: -0.68, 95% CI = -0.98 to -0.39, p < .001, d = 3.75; CGI-S Clinician: -0.79, 95% CI = -0.95 to -0.62, p < .001; d = 7.71). Functional impairment decreased significantly in the CBT group according to parents (Weiss Functional Impairment Scale -4.02, 95% CI = -7.76 to -0.29, p < .05, d = 2.29) and according to the blinded evaluator (GAF: -7.58, 95% CI = -9.1 to -6.05, p < .001, d = 7.51). CONCLUSION: Group CBT associated with pharmacological treatment is an efficacious intervention for reducing ADHD symptoms and functional impairment in adolescents. Clinical trial registration information-CBT Group for Adolescents With ADHD: a Randomized Controlled Trial; http://clinicaltrials.gov/; NCT02172183. CI - Copyright (c) 2015 American Academy of Child and Adolescent Psychiatry. Published by Elsevier Inc. All rights reserved. FAU - Vidal, Raquel AU - Vidal R AD - Hospital Universitari Vall d'Hebron, ADHD (Attention-Deficit/Hyperactivity Disorder) Program, Centro de Investigacion Biomedica En Red de Salud Mental (CIBERSAM), Barcelona, Spain, and Universitat Autonoma de Barcelona. FAU - Castells, Jordi AU - Castells J AD - Hospital Clinic of Barcelona. FAU - Richarte, Vanesa AU - Richarte V AD - Hospital Universitari Vall d'Hebron, ADHD Program, Barcelona, Spain. FAU - Palomar, Gloria AU - Palomar G AD - Hospital Universitari Vall d'Hebron, ADHD Program, Barcelona, Spain. FAU - Garcia, Marta AU - Garcia M AD - Hospital Clinic of Barcelona. FAU - Nicolau, Rosa AU - Nicolau R AD - Hospital Clinic of Barcelona. FAU - Lazaro, Luisa AU - Lazaro L AD - Hospital Clinic of Barcelona, (CIBERSAM), Institut d'Investigacions Biomediques August Pi i Sunyer (IDIBAPS) and with the University of Barcelona. FAU - Casas, Miguel AU - Casas M AD - Hospital Universitari Vall d'Hebron, ADHD (Attention-Deficit/Hyperactivity Disorder) Program, Centro de Investigacion Biomedica En Red de Salud Mental (CIBERSAM), Barcelona, Spain, and Universitat Autonoma de Barcelona. FAU - Ramos-Quiroga, Josep Antoni AU - Ramos-Quiroga JA AD - Hospital Universitari Vall d'Hebron, ADHD (Attention-Deficit/Hyperactivity Disorder) Program, Centro de Investigacion Biomedica En Red de Salud Mental (CIBERSAM), Barcelona, Spain, and Universitat Autonoma de Barcelona. Electronic address: jaramos@vhebron.net. LA - eng SI - ClinicalTrials.gov/NCT02172183 PT - Journal Article PT - Multicenter Study PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't DEP - 20150126 PL - United States TA - J Am Acad Child Adolesc Psychiatry JT - Journal of the American Academy of Child and Adolescent Psychiatry JID - 8704565 SB - IM CIN - Evid Based Ment Health. 2015 Nov;18(4):125. PMID: 26363039 EIN - J Am Acad Child Adolesc Psychiatry. 2017 Nov;56(11):1000-1001. PMID: 29096763 MH - Adolescent MH - Adult MH - Attention Deficit Disorder with Hyperactivity/diagnosis/*therapy MH - Cognitive Behavioral Therapy/*methods MH - Female MH - Humans MH - Male MH - Psychiatric Status Rating Scales MH - Psychotherapy, Group/*methods MH - Self Report MH - Severity of Illness Index MH - Single-Blind Method MH - Spain MH - Treatment Outcome MH - Young Adult OTO - NOTNLM OT - ADHD OT - cognitive-behavioral therapy OT - group therapy OT - psychological treatment EDAT- 2015/03/21 06:00 MHDA- 2016/12/16 06:00 CRDT- 2015/03/21 06:00 PHST- 2014/06/24 00:00 [received] PHST- 2014/12/15 00:00 [revised] PHST- 2015/01/21 00:00 [accepted] PHST- 2015/03/21 06:00 [entrez] PHST- 2015/03/21 06:00 [pubmed] PHST- 2016/12/16 06:00 [medline] AID - S0890-8567(15)00036-2 [pii] AID - 10.1016/j.jaac.2014.12.016 [doi] PST - ppublish SO - J Am Acad Child Adolesc Psychiatry. 2015 Apr;54(4):275-82. doi: 10.1016/j.jaac.2014.12.016. Epub 2015 Jan 26.