PMID- 25797719
OWN - NLM
STAT- MEDLINE
DCOM- 20151214
LR  - 20191210
IS  - 1873-376X (Electronic)
IS  - 1570-0232 (Linking)
VI  - 989
DP  - 2015 May 1
TI  - Simultaneous determination of 18 preservative residues in vegetables by ultra 
      high performance liquid chromatography coupled with triple quadrupole/linear ion 
      trap mass spectrometry using a dispersive-SPE procedure.
PG  - 21-6
LID - S1570-0232(15)00129-4 [pii]
LID - 10.1016/j.jchromb.2015.02.030 [doi]
AB  - A new method combining dispersive-solid phase purification procedure with ultra 
      high performance liquid chromatography-triple quadrupole/linear ion trap mass 
      spectrometry was developed for simultaneous determination of 18 preservative 
      residues in vegetables. The new method not only had the advantages of 
      dispersive-solid phase purification procedure such as high recoveries, easy 
      operation, rapid analysis, little solvent usage and wide analysis range of 
      preservatives, but also had the advantages of ultra high performance liquid 
      chromatography-triple quadrupole/linear ion trap mass spectrometry to be operated 
      in positive mode and negative mode simultaneously. The method was validated for 
      the following representative matrices: radish (tuber), tomato (eggplant fruit), 
      cabbage (leafy), cowpea (bean), cucumber (melon) and so on. Samples were 
      extracted with hexane-ethyl acetate (1:2, v/v), and then detected by ultra high 
      performance liquid chromatography-triple quadrupole/linear ion trap mass 
      spectrometry after being cleaned up with dispersive-solid phase purification 
      procedure. Significant matrix effects were compensated by using the 
      matrix-matched calibration curves. 18 preservatives showed good linearity over 
      the range of 5.0-100.0 mug/L with correlation coefficients of 0.9904-1.000. The 
      limits of detections were in the range of 0.04-4.16 mug/kg and the limits of 
      quantity were in the range of 0.13-13.85 mug/kg. The recoveries of 18 
      preservatives ranged from 76.0% to 120.0% with the spiked levels of 2, 4 and 10 
      mug/kg into homogenized vegetables, and the relative standard deviations (RSDs) 
      ranged from 0.3% to 14.8%. Compared with the reported literatures, the method is 
      more rapid, simple, highly sensitive, reliable and can meet testing requirements 
      of 18 preservative residues in vegetables.
CI  - Copyright (c) 2015 Elsevier B.V. All rights reserved.
FAU - Zhou, Xue
AU  - Zhou X
AD  - College of Pharmacy, Chongqing Medical University, Chongqing 400016, China.
FAU - Cao, Shurui
AU  - Cao S
AD  - Chongqing Entry-Exit Inspection and Quarantine Bureau, Chongqing Engineering 
      Technology Research Center of Import and Export Food Safety, Chongqing 400020, 
      China.
FAU - Li, Xianliang
AU  - Li X
AD  - Chongqing Entry-Exit Inspection and Quarantine Bureau, Chongqing Engineering 
      Technology Research Center of Import and Export Food Safety, Chongqing 400020, 
      China.
FAU - Tang, Bobin
AU  - Tang B
AD  - Chongqing Entry-Exit Inspection and Quarantine Bureau, Chongqing Engineering 
      Technology Research Center of Import and Export Food Safety, Chongqing 400020, 
      China.
FAU - Ding, Xiaowen
AU  - Ding X
AD  - College of Food Science and Engineering, Southwest University, Chongqing 400715, 
      China.
FAU - Xi, Cunxian
AU  - Xi C
AD  - Chongqing Entry-Exit Inspection and Quarantine Bureau, Chongqing Engineering 
      Technology Research Center of Import and Export Food Safety, Chongqing 400020, 
      China.
FAU - Hu, Jiangtao
AU  - Hu J
AD  - Sichuan Entry-Exit Inspection and Quarantine Bureau, Sichuan Engineering 
      Technology Research Center of Import and Export Food Safety, Chengdu 610041, 
      China.
FAU - Chen, Zhiqiong
AU  - Chen Z
AD  - College of Pharmacy, Chongqing Medical University, Chongqing 400016, China.
LA  - eng
PT  - Evaluation Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20150310
PL  - Netherlands
TA  - J Chromatogr B Analyt Technol Biomed Life Sci
JT  - Journal of chromatography. B, Analytical technologies in the biomedical and life 
      sciences
JID - 101139554
RN  - 0 (Food Preservatives)
SB  - IM
MH  - Chromatography, High Pressure Liquid/*methods
MH  - Food Preservatives/*chemistry/isolation & purification
MH  - Fruit/*chemistry
MH  - Solid Phase Extraction/*methods
MH  - Tandem Mass Spectrometry/*methods
MH  - Vegetables/*chemistry
OTO - NOTNLM
OT  - Dispersive-SPE
OT  - Preservatives
OT  - UHPLC-QTRAP
OT  - Vegetables
EDAT- 2015/03/24 06:00
MHDA- 2015/12/15 06:00
CRDT- 2015/03/24 06:00
PHST- 2014/12/02 00:00 [received]
PHST- 2015/02/19 00:00 [revised]
PHST- 2015/02/21 00:00 [accepted]
PHST- 2015/03/24 06:00 [entrez]
PHST- 2015/03/24 06:00 [pubmed]
PHST- 2015/12/15 06:00 [medline]
AID - S1570-0232(15)00129-4 [pii]
AID - 10.1016/j.jchromb.2015.02.030 [doi]
PST - ppublish
SO  - J Chromatogr B Analyt Technol Biomed Life Sci. 2015 May 1;989:21-6. doi: 
      10.1016/j.jchromb.2015.02.030. Epub 2015 Mar 10.