PMID- 2579800 OWN - NLM STAT- MEDLINE DCOM- 19850429 LR - 20190721 IS - 0013-4694 (Print) IS - 0013-4694 (Linking) VI - 60 IP - 4 DP - 1985 Apr TI - Decrement of somatosensory evoked potentials during repetitive stimulation. PG - 335-42 AB - In normal subjects, cerebral potentials were evoked by brief, passive extension of the wrist joint at various interstimulus intervals (ISIs). The resulting somatosensory evoked potentials (SEPs) were found to decrease during repetitive stimulation. The greatest decrement occurred between the first and second responses of each series. After cessation of stimuli, the SEP amplitude returned to control values over a prolonged, exponential time course. The authors postulate that the observed response decrement may be a form of habituation, which provides a model for studying the neuronal substrates of behavior. FAU - Angel, R W AU - Angel RW FAU - Quick, W M AU - Quick WM FAU - Boylls, C C AU - Boylls CC FAU - Weinrich, M AU - Weinrich M FAU - Rodnitzky, R L AU - Rodnitzky RL LA - eng PT - Clinical Trial PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, U.S. Gov't, Non-P.H.S. PL - Ireland TA - Electroencephalogr Clin Neurophysiol JT - Electroencephalography and clinical neurophysiology JID - 0375035 SB - IM MH - Adult MH - Brain/*physiology MH - Electric Stimulation/methods MH - Electroencephalography MH - *Evoked Potentials, Somatosensory MH - Female MH - Humans MH - Male MH - Middle Aged EDAT- 1985/04/01 00:00 MHDA- 1985/04/01 00:01 CRDT- 1985/04/01 00:00 PHST- 1985/04/01 00:00 [pubmed] PHST- 1985/04/01 00:01 [medline] PHST- 1985/04/01 00:00 [entrez] AID - 0013-4694(85)90007-0 [pii] AID - 10.1016/0013-4694(85)90007-0 [doi] PST - ppublish SO - Electroencephalogr Clin Neurophysiol. 1985 Apr;60(4):335-42. doi: 10.1016/0013-4694(85)90007-0.