PMID- 25810263 OWN - NLM STAT- MEDLINE DCOM- 20150911 LR - 20240103 IS - 1545-5017 (Electronic) IS - 1545-5009 (Print) IS - 1545-5009 (Linking) VI - 62 IP - 8 DP - 2015 Aug TI - SIOP-PODC adapted risk stratification and treatment guidelines: Recommendations for neuroblastoma in low- and middle-income settings. PG - 1305-16 LID - 10.1002/pbc.25501 [doi] AB - Neuroblastoma is the most common extracranial solid tumor in childhood in high-income countries (HIC), where consistent treatment approaches based on clinical and tumor biological risk stratification have steadily improved outcomes. However, in low- and middle- income countries (LMIC), suboptimal diagnosis, risk stratification, and treatment may occur due to limited resources and unavailable infrastructure. The clinical practice guidelines outlined in this manuscript are based on current published evidence and expert opinions. Standard risk stratification and treatment explicitly adapted to graduated resource settings can improve outcomes for children with neuroblastoma by reducing preventable toxic death and relapse. CI - (c) 2015 The Authors. Pediatric Blood & Cancer, published by Wiley Periodicals, Inc. FAU - Parikh, Nehal S AU - Parikh NS AD - Department of Pediatrics, Division of Hematology-Oncology, Connecticut Children's Medical Center, Hartford, Connecticut. FAU - Howard, Scott C AU - Howard SC AD - University of Memphis, Memphis, Tennessee. FAU - Chantada, Guillermo AU - Chantada G AD - Department of Hemato-oncology, Hospital JP Garrahan, Buenos Aires, Argentina. FAU - Israels, Trijn AU - Israels T AD - VU University Medical Center, Amsterdam, the Netherlands. FAU - Khattab, Mohammed AU - Khattab M AD - Department of Paediatrics, Children's Hospital of Rabat, Rabat, Morocco. FAU - Alcasabas, Patricia AU - Alcasabas P AD - University of the Philippines-Philippine General Hospital, Manila, Philippines. FAU - Lam, Catherine G AU - Lam CG AD - Department of Oncology and International Outreach Program, St. Jude Children's Research Hospital, Memphis, Tennessee. FAU - Faulkner, Lawrence AU - Faulkner L AD - Cure2Children Foundation, Florence, Italy. FAU - Park, Julie R AU - Park JR AD - Seattle Children's Hospital, University of Washington School of Medicine and Fred Hutchinson Cancer Research Center, Seattle, Washington. FAU - London, Wendy B AU - London WB AD - Harvard Medical School, Boston Children's Hospital and Dana Farber Cancer Institute, Boston, Maryland. FAU - Matthay, Katherine K AU - Matthay KK AD - Department of Pediatrics, UCSF School of Medicine and UCSF Benioff Children's Hospital, San Francisco, California. CN - International Society of Pediatric Oncology LA - eng PT - Journal Article PT - Practice Guideline PT - Research Support, Non-U.S. Gov't DEP - 20150321 PL - United States TA - Pediatr Blood Cancer JT - Pediatric blood & cancer JID - 101186624 SB - IM MH - *Developing Countries MH - Humans MH - Infant MH - Infant, Newborn MH - Neoplasm Recurrence, Local/diagnostic imaging/*mortality MH - Neoplasm Staging MH - Neuroblastoma/*diagnosis/diagnostic imaging/*drug therapy MH - Poverty MH - Radiography MH - Radionuclide Imaging MH - Risk MH - Socioeconomic Factors PMC - PMC5132052 OTO - NOTNLM OT - MYCN OT - Neuroblastoma OT - diagnosis OT - low income countries OT - resource limited countries OT - treatment EDAT- 2015/03/27 06:00 MHDA- 2015/09/12 06:00 PMCR- 2016/12/01 CRDT- 2015/03/27 06:00 PHST- 2014/11/12 00:00 [received] PHST- 2015/01/30 00:00 [accepted] PHST- 2015/03/27 06:00 [entrez] PHST- 2015/03/27 06:00 [pubmed] PHST- 2015/09/12 06:00 [medline] PHST- 2016/12/01 00:00 [pmc-release] AID - PBC25501 [pii] AID - 10.1002/pbc.25501 [doi] PST - ppublish SO - Pediatr Blood Cancer. 2015 Aug;62(8):1305-16. doi: 10.1002/pbc.25501. Epub 2015 Mar 21.