PMID- 25810981
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20150326
LR  - 20200930
IS  - 2249-4863 (Print)
IS  - 2278-7135 (Electronic)
IS  - 2249-4863 (Linking)
VI  - 4
IP  - 1
DP  - 2015 Jan-Mar
TI  - Four new vaccines for routine immunization in India: what about hemophilus 
      influenza B and pneumococcal vaccine?
PG  - 9-12
LID - 10.4103/2249-4863.152238 [doi]
AB  - Immunization is the process whereby a person is made immune or resistant to an 
      infectious disease, typically by the administration of a vaccine. The Expanded 
      Program on Immunization (EPI) was flagged off in India in 1978. According to the 
      recommendation of National technical advisory group of India (NATGI), Government 
      of India is going to include four new vaccines in the UIP for whole India. The 
      four new vaccines are Inactivated Poliomyelitis Vaccine (IPV) for polio, rota 
      viral vaccine, vaccine against rubella, and Japanese encephalitis vaccine (179 
      districts in India). Here, authors have tried to show a comparative descriptive 
      analysis of the hemophilus influenza and pneumococcal pneumonia with rota virus, 
      so that in near future Government of India can also consider their inclusion in 
      the national UIP. In India, 39.2% of all diarrheal death are due to rota virus, 
      whereas 0.72 million deaths are due to hemophilus influenza B and 1.3 million are 
      due to pneumococcal pneumonia in <5 years age-group. India's indigenous developed 
      rota viral vaccine's (Rotavac) efficacy is 56% in 1(st) year compared to H 
      influenza B (Hib) efficacy 95% and PCV13 vaccine "3 + 1" dose efficacy 100% 
      (South Africa). Rotarix incremental cost-effectiveness ratio is US $21.4 to US 
      $34 per disability-adjusted life years (DALYs) compared to Hib US $ 819 per DALYs 
      in India. In case of pneumococcal vaccine, India needs more trails on the 
      serotype specificity, efficacy, and cost-effectiveness but there is enough 
      evidence that hemophilus influenza burden is high in India and the present Hib 
      vaccine is safe and highly effective. In future with the help of donor agencies, 
      India should include the hemophilus influenza B and pneumococcal pneumonia 
      vaccine in national UIP which will save millions of poor children's life.
FAU - Paul, Sourabh
AU  - Paul S
AD  - Department of Community Medicine and Family Medicine, All India Institute of 
      Medical Sciences, Bhubaneswar, Odisha, India.
FAU - Sahoo, Jyotiranjan
AU  - Sahoo J
AD  - Department of Community Medicine and Family Medicine, All India Institute of 
      Medical Sciences, Bhubaneswar, Odisha, India.
LA  - eng
PT  - Journal Article
PL  - India
TA  - J Family Med Prim Care
JT  - Journal of family medicine and primary care
JID - 101610082
CON - J Family Med Prim Care. 4(1):3.
PMC - PMC4367014
OTO - NOTNLM
OT  - Hib
OT  - PCV13
OT  - rotavac
OT  - universal immunization program
COIS- Conflict of Interest: None declared.
EDAT- 2015/03/27 06:00
MHDA- 2015/03/27 06:01
PMCR- 2015/01/01
CRDT- 2015/03/27 06:00
PHST- 2015/03/27 06:00 [entrez]
PHST- 2015/03/27 06:00 [pubmed]
PHST- 2015/03/27 06:01 [medline]
PHST- 2015/01/01 00:00 [pmc-release]
AID - JFMPC-4-9 [pii]
AID - 10.4103/2249-4863.152238 [doi]
PST - ppublish
SO  - J Family Med Prim Care. 2015 Jan-Mar;4(1):9-12. doi: 10.4103/2249-4863.152238.