PMID- 25815265
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20150327
LR  - 20200930
IS  - 2220-3206 (Print)
IS  - 2220-3206 (Electronic)
IS  - 2220-3206 (Linking)
VI  - 5
IP  - 1
DP  - 2015 Mar 22
TI  - Brain-derived neurotrophic factor levels in first episode of psychosis: A 
      systematic review.
PG  - 154-9
LID - 10.5498/wjp.v5.i1.154 [doi]
AB  - AIM: To systematically review studies measuring peripheric brain-derived 
      neurotrophic factor (BDNF) levels on first-episode psychosis patients and 
      variables related to them. METHODS: A systematic search was made of articles 
      published in the Medline database from 2002 up to June 2014. Included are 
      original studies that report enzyme-linked immunosorbent assay measurement of 
      BDNF levels in serum or plasma in patients with a diagnosis of first episode 
      psychosis (FEP) and age- and gender- matched healthy controls. RESULTS: Of the 
      initially identified 147 articles, only 18 satisfied the inclusion criteria. Of 
      this, 15 found a significant reduction in patients with FEP compared with age- 
      and gender - matched controls. CONCLUSION: Peripheral BDNF levels are generally 
      reduced in FEP patients. There are some factors that may influence BDNF levels 
      that need to be further studied. Furthermore, a future meta-analysis in this 
      topic is needed.
FAU - Toll, Alba
AU  - Toll A
AD  - Alba Toll, Anna Mane, Institut de Neuropsiquitria i Addiccions, Parc de Salut 
      Mar, 08003 Barcelona, Spain.
FAU - Mane, Anna
AU  - Mane A
AD  - Alba Toll, Anna Mane, Institut de Neuropsiquitria i Addiccions, Parc de Salut 
      Mar, 08003 Barcelona, Spain.
LA  - eng
PT  - Journal Article
PL  - United States
TA  - World J Psychiatry
JT  - World journal of psychiatry
JID - 101610480
PMC - PMC4369546
OTO - NOTNLM
OT  - Brain-derived neurotrophic factor
OT  - Psychosis
EDAT- 2015/03/31 06:00
MHDA- 2015/03/31 06:01
PMCR- 2015/03/22
CRDT- 2015/03/28 06:00
PHST- 2014/09/29 00:00 [received]
PHST- 2015/01/08 00:00 [revised]
PHST- 2015/01/30 00:00 [accepted]
PHST- 2015/03/28 06:00 [entrez]
PHST- 2015/03/31 06:00 [pubmed]
PHST- 2015/03/31 06:01 [medline]
PHST- 2015/03/22 00:00 [pmc-release]
AID - 10.5498/wjp.v5.i1.154 [doi]
PST - ppublish
SO  - World J Psychiatry. 2015 Mar 22;5(1):154-9. doi: 10.5498/wjp.v5.i1.154.