PMID- 2581757
OWN - NLM
STAT- MEDLINE
DCOM- 19850703
LR  - 20190721
IS  - 0013-4694 (Print)
IS  - 0013-4694 (Linking)
VI  - 62
IP  - 3
DP  - 1985 May
TI  - The effect of age, sex and interstimulus interval on augmenting and reducing of 
      occipital VEPs.
PG  - 177-83
AB  - Three intensities of patterned and unpatterned flashes were used to elicit 
      occipital visually evoked potentials (VEPs) from 4 groups of 15 subjects: boys 
      and girls aged 7-9 years and boys and 15 girls aged 13-15 years. Interstimulus 
      intervals (ISIs) of 1, 2 and 4 sec were used. Amplitude/intensity (A/I) slope was 
      computed for each ISI and flash type condition and an estimate was made of the 
      ability to differentiate patterned from unpatterned stimuli. The latter was 
      inferred from coefficients of correlation which reflected the degree of 
      similarity between VEP wave forms elicited by the two types of flashes. Responses 
      of younger children attenuated to increasing stimulus intensity (negative A/I 
      slope), while VEP amplitude of older subjects augmented to brighter flashes. VEP 
      amplitude reduction may be the response of an immature brain to overstimulation. 
      Amplitude reducing by 7-9-year-old children does not appear to be related to 
      insufficient time between flashes for visual system recovery, since ISI did not 
      differentially affect A/I slope of the younger and older subjects. Longer ISIs 
      did, however, tend to produce more positive A/I slopes for all subjects, but only 
      for patterned stimuli, suggesting that pattern detectors do not fully recover 
      with ISIs of 1 and 2 sec. The visual system of young children was relatively less 
      efficient than that of older children at differentiating patterned from 
      unpatterned stimuli, indicating a differential sensitivity of pattern detectors 
      as a function of age. Gender was not a factor in either magnitude of A/I slope or 
      similarity of VEP wave forms.
FAU - Cohn, N B
AU  - Cohn NB
FAU - Dustman, R E
AU  - Dustman RE
FAU - Shearer, D E
AU  - Shearer DE
LA  - eng
GR  - AG00568/AG/NIA NIH HHS/United States
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, U.S. Gov't, Non-P.H.S.
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - Ireland
TA  - Electroencephalogr Clin Neurophysiol
JT  - Electroencephalography and clinical neurophysiology
JID - 0375035
SB  - IM
MH  - Adolescent
MH  - Age Factors
MH  - Child
MH  - *Evoked Potentials, Visual
MH  - Female
MH  - Humans
MH  - Male
MH  - Occipital Lobe/*physiopathology
MH  - Photic Stimulation
MH  - Reaction Time
MH  - Sex Factors
MH  - Time Factors
EDAT- 1985/05/01 00:00
MHDA- 1985/05/01 00:01
CRDT- 1985/05/01 00:00
PHST- 1985/05/01 00:00 [pubmed]
PHST- 1985/05/01 00:01 [medline]
PHST- 1985/05/01 00:00 [entrez]
AID - 10.1016/0168-5597(85)90012-7 [doi]
PST - ppublish
SO  - Electroencephalogr Clin Neurophysiol. 1985 May;62(3):177-83. doi: 
      10.1016/0168-5597(85)90012-7.