PMID- 25819922 OWN - NLM STAT- MEDLINE DCOM- 20151217 LR - 20220817 IS - 0020-6539 (Print) IS - 1875-595X (Electronic) IS - 0020-6539 (Linking) VI - 65 IP - 3 DP - 2015 Jun TI - Oral allergy syndrome in children. PG - 164-8 LID - 10.1111/idj.12164 [doi] AB - Oral allergy syndrome (OAS) is an allergic reaction that occurs after consumption of fresh fruits and vegetables in patients with allergy to pollen. It is mediated by immunoglobulin E (IgE) antibodies and symptoms arise as a result of cross-reactivity between pollen and plant-derived food. OAS is rarely seen in young children, but the prevalence increases with age. The objectives of the study were to identify the prevalence of OAS and probable risk factors in children and adolescents with seasonal allergic rhinitis (AR). One-hundred and twenty patients with seasonal AR were included. Patients were diagnosed based on their clinical history, skin prick test outcome and specific IgE. In patients describing OAS, prick-by-prick tests with fresh fruit or vegetables were carried out. Thirty-two patients had OAS and it was more frequent in female patients than in male patients. OAS was more frequent in adolescents than in small children and in patients with higher total IgE. OAS was significantly more prevalent in patients with AR and asthma (P=0.0016), as was the case in patients with AR and atopic dermatitis (P=0.0004). OAS is rarely diagnosed in small children, partly because of an inadequate clinical history. Patients with OAS may have some risk factors in addition to pollen allergy, and those with more severe atopy are more likely to develop OAS. CI - (c) 2015 FDI World Dental Federation. FAU - Ivkovic-Jurekovic, Irena AU - Ivkovic-Jurekovic I AD - Pediatric Clinic, Department of Pulmonology, Allergology, Immunology and Rheumatology, Children's Hospital Zagreb, Zagreb, Croatia. LA - eng PT - Comparative Study PT - Journal Article DEP - 20150326 PL - England TA - Int Dent J JT - International dental journal JID - 0374714 RN - 0 (Allergens) RN - 37341-29-0 (Immunoglobulin E) SB - IM MH - Adolescent MH - Age Factors MH - Allergens/immunology MH - Asthma/immunology MH - Child MH - Child, Preschool MH - Cross Reactions MH - Dermatitis, Atopic/immunology MH - Female MH - Food Hypersensitivity/*diagnosis/immunology MH - Fruit MH - Humans MH - Immunoglobulin E/analysis MH - Male MH - Pollen MH - Rhinitis, Allergic, Seasonal/*diagnosis/immunology MH - Sex Factors MH - Skin Tests MH - Vegetables PMC - PMC9376504 OTO - NOTNLM OT - Allergic rhinitis OT - children OT - oral allergy syndrome OT - pollen food allergy syndrome EDAT- 2015/03/31 06:00 MHDA- 2015/12/19 06:00 PMCR- 2020/11/02 CRDT- 2015/03/31 06:00 PHST- 2015/03/31 06:00 [entrez] PHST- 2015/03/31 06:00 [pubmed] PHST- 2015/12/19 06:00 [medline] PHST- 2020/11/02 00:00 [pmc-release] AID - S0020-6539(20)32694-0 [pii] AID - 10.1111/idj.12164 [doi] PST - ppublish SO - Int Dent J. 2015 Jun;65(3):164-8. doi: 10.1111/idj.12164. Epub 2015 Mar 26.