PMID- 25823467
OWN - NLM
STAT- MEDLINE
DCOM- 20161020
LR  - 20181202
IS  - 1087-1640 (Print)
IS  - 1087-1640 (Linking)
VI  - 20
IP  - 1
DP  - 2016 Jan
TI  - BDNF Val66Met is Associated With Performance in a Computerized Visual-Motor 
      Tracking Test In Healthy Adults.
PG  - 122-34
LID - 10.1123/mc.2014-0075 [doi]
AB  - The brain-derived neurotrophic factor gene (BDNF) is known to play an important 
      role in neuroplasticity and cognitive processes. We explored the association of 
      BDNF Val66Met polymorphism with performance in a visual-motor tracking test. One 
      hundred and sixty-seven young, healthy Colombian adults completed a computerized 
      version of the Pursuit Rotor Task, using the Psychology Experiment Building 
      Language (PEBL) platform. DNA genotyping was performed by allele-specific 
      polymerase chain reaction. We found that BDNF Val/Met and Met/Met subjects 
      performed better in the pursuit rotor task (p = .03). Our findings suggest that 
      the BDNF gene is essential to understand differences in motor performance in 
      healthy participants in different populations. This approach could be useful for 
      future fine mapping of genetic modifiers for neuropsychiatric diseases.
FAU - Gonzalez-Giraldo, Yeimy
AU  - Gonzalez-Giraldo Y
AD  - Laboratory of NeuroPsychiatric Genetics, Biomedical Sciences Research Group, 
      School of Medicine, Universidad Antonio Narino, Bogota, Colombia.
FAU - Rojas, Johana
AU  - Rojas J
FAU - Mueller, Shane T
AU  - Mueller ST
FAU - Piper, Brian J
AU  - Piper BJ
FAU - Adan, Ana
AU  - Adan A
FAU - Forero, Diego A
AU  - Forero DA
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20150327
PL  - United States
TA  - Motor Control
JT  - Motor control
JID - 9706297
RN  - 0 (Brain-Derived Neurotrophic Factor)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Brain-Derived Neurotrophic Factor/*genetics
MH  - Eye Movements/*physiology
MH  - Female
MH  - Genotype
MH  - Humans
MH  - Learning/physiology
MH  - Male
MH  - Motor Skills/*physiology
MH  - Polymerase Chain Reaction
MH  - *Polymorphism, Genetic
MH  - Psychomotor Performance/*physiology
MH  - Regression Analysis
MH  - Visual Perception/*physiology
MH  - Young Adult
EDAT- 2015/04/01 06:00
MHDA- 2016/10/21 06:00
CRDT- 2015/04/01 06:00
PHST- 2015/04/01 06:00 [entrez]
PHST- 2015/04/01 06:00 [pubmed]
PHST- 2016/10/21 06:00 [medline]
AID - 2014-0075 [pii]
AID - 10.1123/mc.2014-0075 [doi]
PST - ppublish
SO  - Motor Control. 2016 Jan;20(1):122-34. doi: 10.1123/mc.2014-0075. Epub 2015 Mar 
      27.