PMID- 25824100 OWN - NLM STAT- MEDLINE DCOM- 20151012 LR - 20240324 IS - 1523-7052 (Electronic) IS - 1523-7060 (Print) IS - 1523-7052 (Linking) VI - 17 IP - 8 DP - 2015 Apr 17 TI - Efficient isocyanide-less isocyanide-based multicomponent reactions. PG - 2002-5 LID - 10.1021/acs.orglett.5b00759 [doi] AB - Isocyanides are the "Jekyll and Hyde" of organic chemistry allowing for extremely interesting transformations that are not only extremely odorous but also noxious. Therefore, an isocyanide-less isocyanide-based multicomponent reaction (IMCR) has been developed, and this protocol is expected to replace many of the old procedures in the future not only in IMCR but in other areas of organic chemistry as well. FAU - Neochoritis, Constantinos G AU - Neochoritis CG AD - University of Groningen, Department of Drug Design, A. Deusinglaan 1, 9713 AV Groningen, The Netherlands. FAU - Stotani, Silvia AU - Stotani S AD - University of Groningen, Department of Drug Design, A. Deusinglaan 1, 9713 AV Groningen, The Netherlands. FAU - Mishra, Bhupendra AU - Mishra B AD - University of Groningen, Department of Drug Design, A. Deusinglaan 1, 9713 AV Groningen, The Netherlands. FAU - Domling, Alexander AU - Domling A AD - University of Groningen, Department of Drug Design, A. Deusinglaan 1, 9713 AV Groningen, The Netherlands. LA - eng GR - R01 GM097082/GM/NIGMS NIH HHS/United States GR - 1R01GM097082-01/GM/NIGMS NIH HHS/United States PT - Journal Article PT - Research Support, N.I.H., Extramural PT - Research Support, Non-U.S. Gov't DEP - 20150331 PL - United States TA - Org Lett JT - Organic letters JID - 100890393 RN - 0 (Cyanides) SB - IM MH - Cyanides/*chemistry MH - Molecular Structure PMC - PMC4733495 MID - NIHMS688683 EDAT- 2015/04/01 06:00 MHDA- 2015/10/13 06:00 PMCR- 2016/04/17 CRDT- 2015/04/01 06:00 PHST- 2015/04/01 06:00 [entrez] PHST- 2015/04/01 06:00 [pubmed] PHST- 2015/10/13 06:00 [medline] PHST- 2016/04/17 00:00 [pmc-release] AID - 10.1021/acs.orglett.5b00759 [doi] PST - ppublish SO - Org Lett. 2015 Apr 17;17(8):2002-5. doi: 10.1021/acs.orglett.5b00759. Epub 2015 Mar 31.