PMID- 25824155 OWN - NLM STAT- MEDLINE DCOM- 20151027 LR - 20191210 IS - 0167-9228 (Print) IS - 0167-9228 (Linking) VI - 46 IP - 2 DP - 2015 Apr TI - [Frailty in people with intellectual disabilities: operationalization, risks and detection]. PG - 92-103 LID - 10.1007/s12439-015-0126-4 [doi] AB - Although the population with intellectual disabilities (ID) is increasingly growing older, there seems to be an early onset of functional decline in this group, which could be explained by frailty. We used data from the Healthy Aging and Intellectual Disability study (HA-ID) to measure frailty in people with ID. Frailty was measured with an adapted version of the frailty index, consisting of 50 health and age related deficits. We were the first to measure frailty with a frailty index in this population, and therefore its validity, in terms of predictive value, needed to be established. In the current article we provide an overview of the design of the frailty index and its relation with adverse health outcomes. In a nearly representative study population of 982 50-plus older adults with ID, we studied the prevalence of frailty and its validity over a 3-year follow-up period. Results show that people with ID were earlier and more severely frail than people from the general population. Frailty was related to early mortality, to disabilities in daily functioning and mobility, to increased medication use, and increased care intensity, but not to hospitalization. Using a hypothetical model, we identify possible interventions to increase the healthy life years in people with ID. FAU - Schoufour, Josje D AU - Schoufour JD AD - Geneeskunde voor verstandelijk gehandicapten, Huisartsgeneeskunde, Erasmus medisch centrum, P.O. Box 2040, 300 CA, Rotterdam, Nederland, j.schoufour@erasmusmc.nl. FAU - Echteld, Michael A AU - Echteld MA FAU - Evenhuis, Heleen M AU - Evenhuis HM LA - dut PT - Journal Article PT - Validation Study TT - Kwetsbaarheid bij ouderen met een verstandelijke beperking: operationalisering, risico en opsporing. PL - Netherlands TA - Tijdschr Gerontol Geriatr JT - Tijdschrift voor gerontologie en geriatrie JID - 8210346 SB - IM MH - *Activities of Daily Living MH - Aged MH - Aged, 80 and over MH - Aging/*physiology/*psychology MH - Female MH - Follow-Up Studies MH - *Frail Elderly MH - Health Status MH - Humans MH - *Intellectual Disability MH - Male MH - Middle Aged MH - Physical Fitness MH - Prevalence EDAT- 2015/04/01 06:00 MHDA- 2015/10/28 06:00 CRDT- 2015/04/01 06:00 PHST- 2015/04/01 06:00 [entrez] PHST- 2015/04/01 06:00 [pubmed] PHST- 2015/10/28 06:00 [medline] AID - 10.1007/s12439-015-0126-4 [doi] PST - ppublish SO - Tijdschr Gerontol Geriatr. 2015 Apr;46(2):92-103. doi: 10.1007/s12439-015-0126-4.