PMID- 25837214
OWN - NLM
STAT- MEDLINE
DCOM- 20160105
LR  - 20221207
IS  - 1873-1244 (Electronic)
IS  - 0899-9007 (Linking)
VI  - 31
IP  - 5
DP  - 2015 May
TI  - Tomato juice supplementation in young women reduces inflammatory adipokine levels 
      independently of body fat reduction.
PG  - 691-6
LID - S0899-9007(14)00502-4 [pii]
LID - 10.1016/j.nut.2014.11.008 [doi]
AB  - OBJECTIVES: Lycopene is a carotene and phytochemical known to protect against 
      metabolic diseases. It is found in red fruits and vegetables, predominantly 
      tomatoes. This study aimed to show the supplementation effect of tomato juice on 
      indices associated with metabolic health and adipokine profiles in generally 
      healthy people. METHODS: A total of 30 young females (20- to 30-years-old) with a 
      body mass index (BMI) >/= 20 were recruited, of whom 25 completed the entire study. 
      The subjects continued with their normal diet and exercise schedule, but were 
      given 280 mL of tomato juice (containing 32.5 mg of lycopene) daily for 2 mo. 
      Metabolic indices, including anthropometric data and serum levels of glucose, 
      lipids, adipokines, lycopene, and antioxidants, were compared pre- and 
      postintervention. RESULTS: Tomato juice supplementation significantly reduced 
      body weight, body fat, waist circumference, BMI, and serum levels of cholesterol, 
      monocyte chemoattractant protein-1 (MCP-1), and thiobarbituric reactive 
      substances, while significantly increasing serum levels of adiponectin, 
      triglyceride, and lycopene. When subjects were stratified by body fat change, 
      i.e., reduction or non-reduction (including increase or no change), the tomato 
      juice-induced reduction in waist circumference, serum cholesterol, and MCP-1 
      levels and increase in adiponectin and lycopene levels were seen in both 
      subgroups. The changes in waist circumference, cholesterol, MCP-1, and 
      adiponectin levels remained significant after adjusting for each covariable 
      individually, with the exception of lycopene. CONCLUSIONS: These results show 
      that daily tomato juice supplementation reduces waist circumference, as well as 
      serum cholesterol and inflammatory adipokine levels in young healthy women and 
      that these effects are unrelated to body fat changes.
CI  - Copyright (c) 2015 Elsevier Inc. All rights reserved.
FAU - Li, Yu-Fen
AU  - Li YF
AD  - Institute of Biostatistics, China Medical University, Taichung, Taiwan.
FAU - Chang, Ya-Yuan
AU  - Chang YY
AD  - Department of Nutrition, China Medical University, Taichung, Taiwan.
FAU - Huang, Hui-Chi
AU  - Huang HC
AD  - Department of Chinese Pharmaceutical Sciences and Chinese Medicine Resources, 
      China Medical University, Taichung, Taiwan.
FAU - Wu, Yi-Chen
AU  - Wu YC
AD  - Department of Nutrition, China Medical University, Taichung, Taiwan.
FAU - Yang, Mei-Due
AU  - Yang MD
AD  - Department of Clinical Nutrition, China Medical University Hospital, Taichung, 
      Taiwan; Department of Surgery, China Medical University Hospital, Taichung, 
      Taiwan. Electronic address: d5218ymd@yahoo.com.tw.
FAU - Chao, Pei-Min
AU  - Chao PM
AD  - Department of Nutrition, China Medical University, Taichung, Taiwan. Electronic 
      address: pmchao@mail.cmu.edu.tw.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20141213
PL  - United States
TA  - Nutrition
JT  - Nutrition (Burbank, Los Angeles County, Calif.)
JID - 8802712
RN  - 0 (ADIPOQ protein, human)
RN  - 0 (Adipokines)
RN  - 0 (Adiponectin)
RN  - 0 (Antioxidants)
RN  - 0 (Blood Glucose)
RN  - 0 (CCL2 protein, human)
RN  - 0 (Chemokine CCL2)
RN  - 0 (Lipids)
RN  - 0 (Thiobarbituric Acid Reactive Substances)
RN  - 36-88-4 (Carotenoids)
RN  - 97C5T2UQ7J (Cholesterol)
RN  - SB0N2N0WV6 (Lycopene)
SB  - IM
MH  - Adipokines/*blood
MH  - Adiponectin/blood
MH  - Adipose Tissue/drug effects
MH  - Adult
MH  - Anthropometry/methods
MH  - Antioxidants/analysis
MH  - Blood Glucose/drug effects
MH  - Body Mass Index
MH  - Body Weight/drug effects
MH  - Carotenoids/administration & dosage/blood/*pharmacology
MH  - Chemokine CCL2/*blood
MH  - Cholesterol/*blood
MH  - Dietary Supplements
MH  - Female
MH  - Fruit and Vegetable Juices
MH  - Humans
MH  - Inflammation/blood/*diet therapy
MH  - Lipids/blood
MH  - Lycopene
MH  - Solanum lycopersicum/*chemistry
MH  - Thiobarbituric Acid Reactive Substances/analysis
MH  - Waist Circumference/*drug effects
MH  - Young Adult
OTO - NOTNLM
OT  - Adiponectin
OT  - Lycopene
OT  - Monocyte chemoattractant protein-1 (MCP-1)
OT  - Serum cholesterol
OT  - Waist circumference
EDAT- 2015/04/04 06:00
MHDA- 2016/01/06 06:00
CRDT- 2015/04/04 06:00
PHST- 2014/07/17 00:00 [received]
PHST- 2014/11/03 00:00 [revised]
PHST- 2014/11/12 00:00 [accepted]
PHST- 2015/04/04 06:00 [entrez]
PHST- 2015/04/04 06:00 [pubmed]
PHST- 2016/01/06 06:00 [medline]
AID - S0899-9007(14)00502-4 [pii]
AID - 10.1016/j.nut.2014.11.008 [doi]
PST - ppublish
SO  - Nutrition. 2015 May;31(5):691-6. doi: 10.1016/j.nut.2014.11.008. Epub 2014 Dec 
      13.