PMID- 25837640
OWN - NLM
STAT- MEDLINE
DCOM- 20151027
LR  - 20181202
IS  - 1724-6016 (Electronic)
IS  - 1120-6721 (Linking)
VI  - 25
IP  - 5
DP  - 2015 Sep-Oct
TI  - Choroidal and peripapillary retinal nerve fiber layer thickness in adults with 
      anisometropic amblyopia.
PG  - 437-42
LID - 10.5301/ejo.5000594 [doi]
AB  - PURPOSE: To evaluate choroidal thickness, macular thickness, and peripapillary 
      retinal nerve fiber layer (RNFL) thickness in amblyopic eyes compared to fellow 
      and normal control eyes using high-definition spectral-domain optical coherence 
      tomography (SD-OCT). METHODS: Fifty-four without any systemic problem and ocular 
      disease participated in this prospective study. Inclusion criteria included 
      individuals older than 18 years with anisometropic amblyopia. Choroidal 
      thickness, central macular thickness (CMT), and RNFL thickness were measured by 
      using enhanced depth imaging SD-OCT. The choroidal thickness was measured at the 
      fovea and at 500 microm intervals from the foveal center in both temporal and nasal 
      directions. Axial length measurements of the cases were also recorded. RESULTS: 
      Mean peripapillary RNFL thickness of the amblyopic, fellow, and control eyes was 
      107.5 +/- 15.5 microm, 109.3 +/- 12.7 microm, and 108.8 +/- 8.6 microm, respectively (p = 0.343). 
      The average CMT was 231.7 +/- 14.7 microm in amblyopic eyes, 232.5 +/- 15.7 mum in fellow 
      eyes, and 230.8 +/- 14.8 microm in control eyes (p = 0.599). Mean subfoveal choroidal 
      thickness was significantly greater in the amblyopic eyes than in the fellow and 
      control eyes (396.3 +/- 104.3 microm, 361.0 +/- 103.9 microm, 390.6 +/- 91.7 microm). Mean axial 
      measurement in amblyopic eyes was 22.7 +/- 1.3 mm (20.5-26.1), in fellow eyes 23.1 
      +/- 0.9 mm (20.9-25.0), and in control eyes 23.3 +/- 0.9 mm. CONCLUSIONS: In adults 
      with anisometropic amblyopia, subfoveal, temporal, and nasal choroidal thickness 
      of amblyopic eyes are significantly thicker than in fellow eyes. However, no 
      significant differences in peripapillary RNFL thickness or CMT were found between 
      amblyopic and fellow or control eyes.
FAU - Kantarci, Feride Aylin
AU  - Kantarci FA
AD  - Department of Ophthalmology, School of Medicine, Fatih University, Istanbul - 
      Turkey.
FAU - Tatar, Mehmet Gurkan
AU  - Tatar MG
FAU - Uslu, Hasim
AU  - Uslu H
FAU - Colak, Hatice Nur
AU  - Colak HN
FAU - Yildirim, Aydin
AU  - Yildirim A
FAU - Goker, Hasan
AU  - Goker H
FAU - Gurler, Bulent
AU  - Gurler B
LA  - eng
PT  - Comparative Study
PT  - Journal Article
DEP - 20150321
PL  - United States
TA  - Eur J Ophthalmol
JT  - European journal of ophthalmology
JID - 9110772
SB  - IM
EIN - Eur J Ophthalmol. 2016 Dec 29;27(1):113. PMID: 28097644
MH  - Adult
MH  - Aged
MH  - Amblyopia/*complications
MH  - Choroid/*pathology
MH  - Cross-Sectional Studies
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Nerve Fibers/*pathology
MH  - Optic Disk/*pathology
MH  - Organ Size
MH  - Prospective Studies
MH  - Retinal Ganglion Cells/*pathology
MH  - Tomography, Optical Coherence/methods
MH  - Visual Acuity/physiology
MH  - Young Adult
EDAT- 2015/04/04 06:00
MHDA- 2015/10/28 06:00
CRDT- 2015/04/04 06:00
PHST- 2015/02/16 00:00 [accepted]
PHST- 2015/04/04 06:00 [entrez]
PHST- 2015/04/04 06:00 [pubmed]
PHST- 2015/10/28 06:00 [medline]
AID - 829AB44B-0AE5-4102-B671-68CE8A582EBC [pii]
AID - 10.5301/ejo.5000594 [doi]
PST - ppublish
SO  - Eur J Ophthalmol. 2015 Sep-Oct;25(5):437-42. doi: 10.5301/ejo.5000594. Epub 2015 
      Mar 21.