PMID- 25838057
OWN - NLM
STAT- MEDLINE
DCOM- 20160128
LR  - 20150420
IS  - 1773-0597 (Electronic)
IS  - 0181-5512 (Linking)
VI  - 38
IP  - 4
DP  - 2015 Apr
TI  - [Acute Retinal Pigment Epitheliitis: spectral-domain optical coherence tomography 
      findings].
PG  - 333-9
LID - S0181-5512(15)00049-2 [pii]
LID - 10.1016/j.jfo.2015.01.004 [doi]
AB  - PURPOSE: Through a case presentation of Acute Retinal Pigment Epitheliitis (ARPE) 
      we highlight the role of spectral-domain optical coherence tomography (SD-OCT) in 
      the management of this rare entity. MATERIALS AND METHODS: A 29-year-old woman 
      presented for reduced visual acuity in the right eye occurring one week after a 
      viral episode. Fundus examination showed zones of macular hyperpigmentation 
      surrounded by yellowish hypopigmented haloes. Fluorescein angiography noted early 
      hyperfluorescence of the hypopigmented lesions. ICG angiography revealed central 
      hyperfluorescence surrounded by a hypofluorescent halo. SD-OCT showed a linear 
      disruption between the photoreceptor inner/outer segments (IS/OS) and an 
      accumulation of material in the photoreceptor outer segments and retinal pigment 
      epithelium (RPE). Spontaneous normalization of visual acuity was noted after 10 
      weeks. SD-OCT revealed restored and continuous inner segment and outer segment 
      layers and some persistent deposits in the photoreceptor layer. RESULTS: SD-OCT 
      findings suggest that the initial lesion in ARPE is located at the junction 
      between the photoreceptor outer segments and the apical side of the RPE cells. It 
      would correspond to an accumulation of photoreceptor outer segment debris 
      secondary to RPE dysfunction, which can occur as a post-viral reaction. 
      CONCLUSION: SD-OCT provides very specific information about the topography of 
      retinal lesions during ARPE, allowing a better understanding of its pathogenesis.
CI  - Copyright (c) 2015 Elsevier Masson SAS. All rights reserved.
FAU - Benlahbib, M
AU  - Benlahbib M
AD  - Service II, CHNO des XV-XX, 28, rue de Charenton, 75012 Paris, France. Electronic 
      address: benlahbibmanal@yahoo.fr.
FAU - Meziani, L
AU  - Meziani L
AD  - Service II, CHNO des XV-XX, 28, rue de Charenton, 75012 Paris, France.
FAU - Akesbi, J
AU  - Akesbi J
AD  - Service II, CHNO des XV-XX, 28, rue de Charenton, 75012 Paris, France.
FAU - Nordmann, J-P
AU  - Nordmann JP
AD  - Service II, CHNO des XV-XX, 28, rue de Charenton, 75012 Paris, France.
LA  - fre
PT  - Case Reports
PT  - English Abstract
PT  - Journal Article
TT  - Epithelite retinienne aigue : apport de la tomographie par coherence optique en 
      Spectral Domain.
DEP - 20150330
PL  - France
TA  - J Fr Ophtalmol
JT  - Journal francais d'ophtalmologie
JID - 7804128
SB  - IM
MH  - Adult
MH  - Female
MH  - Humans
MH  - *Retinal Pigment Epithelium
MH  - Retinitis/*pathology
MH  - *Tomography, Optical Coherence
OTO - NOTNLM
OT  - Acute retinal pigment epitheliitis
OT  - Angiographie au vert d'indocyanine
OT  - Angiographie a la fluoresceine
OT  - Fluorescein angiography
OT  - Indocyanine green angiography
OT  - Spectral-domain optical coherence tomography
OT  - Tomographie par coherence optique
OT  - Epithelite retinienne aigue
EDAT- 2015/04/04 06:00
MHDA- 2016/01/29 06:00
CRDT- 2015/04/04 06:00
PHST- 2014/10/11 00:00 [received]
PHST- 2015/01/05 00:00 [revised]
PHST- 2015/01/15 00:00 [accepted]
PHST- 2015/04/04 06:00 [entrez]
PHST- 2015/04/04 06:00 [pubmed]
PHST- 2016/01/29 06:00 [medline]
AID - S0181-5512(15)00049-2 [pii]
AID - 10.1016/j.jfo.2015.01.004 [doi]
PST - ppublish
SO  - J Fr Ophtalmol. 2015 Apr;38(4):333-9. doi: 10.1016/j.jfo.2015.01.004. Epub 2015 
      Mar 30.