PMID- 25844857
OWN - NLM
STAT- MEDLINE
DCOM- 20160115
LR  - 20190318
IS  - 1938-162X (Electronic)
IS  - 1062-6050 (Print)
IS  - 1062-6050 (Linking)
VI  - 50
IP  - 6
DP  - 2015 Jun
TI  - Short-Wave Diathermy Pretreatment and Inflammatory Myokine Response After 
      High-Intensity Eccentric Exercise.
PG  - 612-20
LID - 10.4085/1062-6050-50.1.12 [doi]
AB  - CONTEXT: Various modalities have been used to pretreat skeletal muscle to 
      attenuate inflammation. OBJECTIVE: To determine the effects of short-wave 
      diathermy (SWD) preheating treatment on inflammation and stress markers after 
      eccentric exercise. DESIGN: Controlled laboratory study. SETTING: University 
      laboratory setting. PATIENTS OR OTHER PARTICIPANTS: Fifteen male (age = 22 +/- 4.9 
      years, height = 179.75 +/- 9.56 cm, mass = 82.22 +/- 12.67 kg) college-aged students. 
      INTERVENTION(S): Seven participants were selected randomly to receive 40 minutes 
      of SWD heat treatment (HT), and 8 participants served as the control (CON) group 
      and rested without SWD. Both groups completed 7 sets of 10 repetitions of a 
      high-intensity eccentric exercise protocol (EEP) at 120% of the 1-repetition 
      maximum (1-RM) leg extension. MAIN OUTCOME MEASURE(S): We biopsied muscles on 
      days 1, 3 (24 hours post-EEP), and 4 (48 hours post-EEP) and collected blood 
      samples on days 1, 2 (4 hours post-EEP), 3, and 4. We determined 1-RM on day 2 
      (24 hours post-SWD) and measured 1-RM on days 3 and 4. We analyzed the muscle 
      samples for interleukin 6 (IL-6), tumor necrosis factor alpha, and heat shock protein 
      70 and the blood for serum creatine kinase. RESULTS: We found a group x time 
      interaction for intramuscular IL-6 levels after SWD (F2,26 = 7.13, P = .003). The 
      IL-6 decreased in HT (F1,6 = 17.8, P = .006), whereas CON showed no change (P > 
      .05). We found a group x time interaction for tumor necrosis factor alpha levels 
      (F2,26 = 3.71, P = .04), which increased in CON (F2,14 = 7.16, P = .007), but saw 
      no changes for HT (P > .05). No group x time interactions were noted for 1-RM, 
      heat shock protein 70, or creatine kinase (P > .05). CONCLUSIONS: The SWD 
      preheating treatment provided a treatment effect for intramuscular inflammatory 
      myokines induced through high-intensity eccentric exercise but did not affect 
      other factors associated with intense exercise and inflammation.
FAU - Vardiman, John P
AU  - Vardiman JP
AD  - Applied Physiology Laboratory, University of Kansas, Lawrence;
FAU - Moodie, Nicole
AU  - Moodie N
AD  - Exercise and Sport Science Department, Rockhurst University, Kansas City, MO;
FAU - Siedlik, Jacob A
AU  - Siedlik JA
AD  - Applied Physiology Laboratory, University of Kansas, Lawrence;
FAU - Kudrna, Rebecca A
AU  - Kudrna RA
AD  - Desales University, Center Valley, PA.
FAU - Graham, Zachary
AU  - Graham Z
AD  - Applied Physiology Laboratory, University of Kansas, Lawrence;
FAU - Gallagher, Philip
AU  - Gallagher P
AD  - Applied Physiology Laboratory, University of Kansas, Lawrence;
LA  - eng
PT  - Journal Article
PT  - Randomized Controlled Trial
DEP - 20150406
PL  - United States
TA  - J Athl Train
JT  - Journal of athletic training
JID - 9301647
RN  - 0 (Biomarkers)
RN  - 0 (Cytokines)
RN  - 0 (HSP70 Heat-Shock Proteins)
RN  - 0 (IL6 protein, human)
RN  - 0 (Interleukin-6)
RN  - 0 (TNF protein, human)
RN  - 0 (Tumor Necrosis Factor-alpha)
RN  - EC 2.7.3.2 (Creatine Kinase)
SB  - IM
MH  - Biomarkers/metabolism
MH  - Creatine Kinase/metabolism
MH  - Cytokines/*metabolism
MH  - Diathermy/*methods
MH  - Exercise/*physiology
MH  - HSP70 Heat-Shock Proteins/metabolism
MH  - Humans
MH  - Interleukin-6/metabolism
MH  - Male
MH  - Muscle, Skeletal/*physiology
MH  - Myositis/physiopathology
MH  - Tumor Necrosis Factor-alpha/blood/metabolism
MH  - Young Adult
PMC - PMC4527445
OTO - NOTNLM
OT  - cytokines
OT  - inflammation
OT  - interleukin-6
OT  - tumor necrosis factor alpha
EDAT- 2015/04/07 06:00
MHDA- 2016/01/16 06:00
PMCR- 2016/06/01
CRDT- 2015/04/07 06:00
PHST- 2015/04/07 06:00 [entrez]
PHST- 2015/04/07 06:00 [pubmed]
PHST- 2016/01/16 06:00 [medline]
PHST- 2016/06/01 00:00 [pmc-release]
AID - 10.4085/1062-6050-50.1.12 [doi]
PST - ppublish
SO  - J Athl Train. 2015 Jun;50(6):612-20. doi: 10.4085/1062-6050-50.1.12. Epub 2015 
      Apr 6.