PMID- 25847772
OWN - NLM
STAT- MEDLINE
DCOM- 20161230
LR  - 20181113
IS  - 1993-0402 (Electronic)
IS  - 1672-0415 (Linking)
VI  - 22
IP  - 4
DP  - 2016 Apr
TI  - Acupuncture treatment modulates the resting-state functional connectivity of 
      brain regions in migraine patients without aura.
PG  - 293-301
LID - 10.1007/s11655-015-2042-4 [doi]
AB  - OBJECTIVE: To investigate the modulatory effect of acupuncture treatment on the 
      resting-state functional connectivity of brain regions in migraine without aura 
      (MWoA) patients. METHODS: Twelve MWoA patients were treated with standard 
      acupuncture treatment for 4 weeks. All MWoA patients received resting-state 
      functional magnetic resonance imaging (fMRI) scanning before and after 
      acupuncture treatment. Another 12 normal subjects matched in age and gender were 
      recruited to serve as healthy controls. The changes of restingstate functional 
      connectivity in MWoA patients before and after the acupuncture treatment and 
      those with the healthy controls were compared. RESULTS: Before acupuncture 
      treatment, the MWoA patients had significantly decreased functional connectivity 
      in certain brain regions within the frontal and temporal lobe when compared with 
      the healthy controls. After acupuncture treatment, brain regions showing 
      decreased functional connectivity revealed significant reduction in MWoA patients 
      compared with before acupuncture treatment. CONCLUSIONS: Acupuncture treatment 
      could increase the functional connectivity of brain regions in the intrinsic 
      decreased brain networks in MWoA patients. The results provided further insights 
      into the interpretation of neural mechanisms of acupuncture treatment for 
      migraine.
FAU - Zhang, Yong
AU  - Zhang Y
AD  - Department of Neurology and Stroke Center, Dongzhimen Hospital, the First 
      Affiliated Hospital of Beijing University of Chinese Medicine, Beijing, 100700, 
      China.
FAU - Li, Kuang-shi
AU  - Li KS
AD  - Department of Neurology and Stroke Center, Dongzhimen Hospital, the First 
      Affiliated Hospital of Beijing University of Chinese Medicine, Beijing, 100700, 
      China.
FAU - Liu, Hong-wei
AU  - Liu HW
AD  - Department of Neurology and Stroke Center, Dongzhimen Hospital, the First 
      Affiliated Hospital of Beijing University of Chinese Medicine, Beijing, 100700, 
      China.
FAU - Fu, Cai-hong
AU  - Fu CH
AD  - Department of Neurology and Stroke Center, Dongzhimen Hospital, the First 
      Affiliated Hospital of Beijing University of Chinese Medicine, Beijing, 100700, 
      China.
FAU - Chen, Sheng
AU  - Chen S
AD  - Department of Acupuncture, Dongzhimen Hospital, the First Affiliated Hospital of 
      Beijing University of Chinese Medicine, Beijing, 100700, China.
FAU - Tan, Zhong-jian
AU  - Tan ZJ
AD  - Department of Magnetic Resonance Imaging, Dongzhimen Hospital, the First 
      Affiliated Hospital of Beijing University of Chinese Medicine, Beijing, 100700, 
      China.
FAU - Ren, Yi
AU  - Ren Y
AD  - Department of Neurology and Stroke Center, Dongzhimen Hospital, the First 
      Affiliated Hospital of Beijing University of Chinese Medicine, Beijing, 100700, 
      China. rywendy1982@sina.com.
LA  - eng
PT  - Clinical Trial
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20150406
PL  - China
TA  - Chin J Integr Med
JT  - Chinese journal of integrative medicine
JID - 101181180
SB  - IM
MH  - *Acupuncture Therapy
MH  - Brain/*physiopathology
MH  - Case-Control Studies
MH  - Demography
MH  - Female
MH  - Humans
MH  - Magnetic Resonance Imaging
MH  - Male
MH  - Migraine without Aura/*physiopathology
MH  - Nerve Net/*physiopathology
MH  - *Rest
MH  - Treatment Outcome
OTO - NOTNLM
OT  - acupuncture
OT  - functional connectivity
OT  - functional magnetic resonance imaging
OT  - migraine without aura
OT  - resting-state
EDAT- 2015/04/08 06:00
MHDA- 2016/12/31 06:00
CRDT- 2015/04/08 06:00
PHST- 2014/10/26 00:00 [received]
PHST- 2015/04/08 06:00 [entrez]
PHST- 2015/04/08 06:00 [pubmed]
PHST- 2016/12/31 06:00 [medline]
AID - 10.1007/s11655-015-2042-4 [pii]
AID - 10.1007/s11655-015-2042-4 [doi]
PST - ppublish
SO  - Chin J Integr Med. 2016 Apr;22(4):293-301. doi: 10.1007/s11655-015-2042-4. Epub 
      2015 Apr 6.