PMID- 25848116
OWN - NLM
STAT- MEDLINE
DCOM- 20160422
LR  - 20150714
IS  - 1742-3406 (Electronic)
IS  - 0144-8420 (Linking)
VI  - 165
IP  - 1-4
DP  - 2015 Jul
TI  - Paediatric CT protocol optimisation: a design of experiments to support the 
      modelling and optimisation process.
PG  - 205-9
LID - 10.1093/rpd/ncv067 [doi]
AB  - In the last decade, several studies have emphasised the need to understand and 
      optimise the computed tomography (CT) procedures in order to reduce the radiation 
      dose applied to paediatric patients. To evaluate the influence of the technical 
      parameters on the radiation dose and the image quality, a statistical model has 
      been developed using the design of experiments (DOE) method that has been 
      successfully used in various fields (industry, biology and finance) applied to CT 
      procedures for the abdomen of paediatric patients. A Box-Behnken DOE was used in 
      this study. Three mathematical models (contrast-to-noise ratio, noise and CTDI 
      vol) depending on three factors (tube current, tube voltage and level of 
      iterative reconstruction) were developed and validated. They will serve as a 
      basis for the development of a CT protocol optimisation model.
CI  - (c) The Author 2015. Published by Oxford University Press. All rights reserved. For 
      Permissions, please email: journals.permissions@oup.com.
FAU - Rani, K
AU  - Rani K
AD  - SANTEC Department, CRP Henri Tudor, 29 Avenue J-f Kennedy, Luxembourg 1855, 
      Luxembourg Universite de Lorraine, CRAN, UMR 7039, 34 Cours Leopold, Nancy 54000, 
      France kaddour.rani@tudor.lu.
FAU - Jahnen, A
AU  - Jahnen A
AD  - SANTEC Department, CRP Henri Tudor, 29 Avenue J-f Kennedy, Luxembourg 1855, 
      Luxembourg.
FAU - Noel, A
AU  - Noel A
AD  - Universite de Lorraine, CRAN, UMR 7039, 34 Cours Leopold, Nancy 54000, France.
FAU - Wolf, D
AU  - Wolf D
AD  - Universite de Lorraine, CRAN, UMR 7039, 34 Cours Leopold, Nancy 54000, France.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20150405
PL  - England
TA  - Radiat Prot Dosimetry
JT  - Radiation protection dosimetry
JID - 8109958
RN  - 0 (Contrast Media)
SB  - IM
MH  - Algorithms
MH  - Analysis of Variance
MH  - Child
MH  - Contrast Media
MH  - Humans
MH  - Models, Statistical
MH  - Multidetector Computed Tomography/*methods/standards
MH  - Pediatrics/*methods
MH  - Phantoms, Imaging
MH  - Radiation Dosage
MH  - Radiation, Ionizing
MH  - Radiographic Image Interpretation, Computer-Assisted/methods
MH  - Research Design
MH  - Signal-To-Noise Ratio
MH  - Tomography Scanners, X-Ray Computed
EDAT- 2015/04/08 06:00
MHDA- 2016/04/23 06:00
CRDT- 2015/04/08 06:00
PHST- 2015/04/08 06:00 [entrez]
PHST- 2015/04/08 06:00 [pubmed]
PHST- 2016/04/23 06:00 [medline]
AID - ncv067 [pii]
AID - 10.1093/rpd/ncv067 [doi]
PST - ppublish
SO  - Radiat Prot Dosimetry. 2015 Jul;165(1-4):205-9. doi: 10.1093/rpd/ncv067. Epub 
      2015 Apr 5.