PMID- 25852695
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20150408
LR  - 20201226
IS  - 1664-3224 (Print)
IS  - 1664-3224 (Electronic)
IS  - 1664-3224 (Linking)
VI  - 6
DP  - 2015
TI  - The known unknowns of the human dendritic cell network.
PG  - 129
LID - 10.3389/fimmu.2015.00129 [doi]
LID - 129
AB  - Dendritic cells (DCs) initiate and orient immune responses and comprise several 
      subsets that display distinct phenotypes and properties. Most of our knowledge of 
      DC subsets biology is based on mouse studies. In the past few years, the 
      alignment of the human DC network with the mouse DC network has been the focus of 
      much attention. Although comparative phenotypic and transcriptomic analysis have 
      shown a high level of homology between mouse and human DC subsets, significant 
      differences in phenotype and function have also been evidenced. Here, we review 
      recent advances in our understanding of the human DC network and discuss some 
      remaining gaps and future challenges of the human DC field.
FAU - Durand, Melanie
AU  - Durand M
AD  - Centre de Recherche, Institut Curie , Paris , France ; INSERM U932 , Paris , 
      France.
FAU - Segura, Elodie
AU  - Segura E
AD  - Centre de Recherche, Institut Curie , Paris , France ; INSERM U932 , Paris , 
      France.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20150323
PL  - Switzerland
TA  - Front Immunol
JT  - Frontiers in immunology
JID - 101560960
PMC - PMC4369872
OTO - NOTNLM
OT  - DC subsets
OT  - antigen presentation
OT  - dendritic cells
OT  - human
OT  - ontogeny
EDAT- 2015/04/09 06:00
MHDA- 2015/04/09 06:01
PMCR- 2015/01/01
CRDT- 2015/04/09 06:00
PHST- 2015/01/14 00:00 [received]
PHST- 2015/03/09 00:00 [accepted]
PHST- 2015/04/09 06:00 [entrez]
PHST- 2015/04/09 06:00 [pubmed]
PHST- 2015/04/09 06:01 [medline]
PHST- 2015/01/01 00:00 [pmc-release]
AID - 10.3389/fimmu.2015.00129 [doi]
PST - epublish
SO  - Front Immunol. 2015 Mar 23;6:129. doi: 10.3389/fimmu.2015.00129. eCollection 
      2015.