PMID- 25856540 OWN - NLM STAT- MEDLINE DCOM- 20160211 LR - 20221207 IS - 1365-2060 (Electronic) IS - 0785-3890 (Print) IS - 0785-3890 (Linking) VI - 47 IP - 3 DP - 2015 May TI - Associations between sleep disturbances and diabetes mellitus among blacks with metabolic syndrome: Results from the Metabolic Syndrome Outcome Study (MetSO). PG - 233-7 LID - 10.3109/07853890.2015.1015601 [doi] AB - INTRODUCTION: The association between sleep disturbances and cardiometabolic diseases has been understudied in blacks with metabolic syndrome. METHODS: This study is a cross-sectional analysis of the Metabolic Syndrome Outcome Study (MetSO) trial. We assessed insomnia symptoms, sleep duration, and risk for sleep apnea. Multivariate logistic regression models evaluated the association between sleep disturbances with diabetes mellitus (DM) and the combined outcomes of DM and hypertension as well as DM and dyslipidemia. RESULTS: The sample consisted of 1,013 participants, mean age of 62 +/- 14 years and 61% female. DM was diagnosed in 60% of the sample. Sleep apnea risk was observed in 48% of the sample, while 10% had insomnia symptoms and 65% reported short sleep duration (< 6 hours). Sleep apnea risk, but not insomnia or sleep duration, was associated with DM (OR 1.66; 95% CI 1.21-2.28), adjusting for age, sex, income, obesity (BMI >/= 30 kg/m(2)), tobacco use, alcohol use, hypertension, dyslipidemia, and depression. In fully adjusted models, sleep apnea risk was associated with the combined outcome of DM-hypertension (OR 1.95; 95% CI 1.42-2.69), but not with diabetes-dyslipidemia. CONCLUSION: We observed a strong association between sleep apnea risk and diabetes mellitus among blacks with metabolic syndrome. FAU - Ramos, Alberto R AU - Ramos AR AD - Department of Neurology, Miller School of Medicine, University of Miami , Miami , FL, USA. FAU - Wallace, Douglas M AU - Wallace DM FAU - Pandi-Perumal, Seithikurippu Ratnas AU - Pandi-Perumal SR FAU - Williams, Natasha J AU - Williams NJ FAU - Castor, Chimene AU - Castor C FAU - Sevick, Mary Ann AU - Sevick MA FAU - Mcfarlane, Samy I AU - Mcfarlane SI FAU - Jean-Louis, Girardin AU - Jean-Louis G LA - eng SI - ClinicalTrials.gov/NCT01946659 GR - R01MD004113/MD/NIMHD NIH HHS/United States GR - R25 HL116378/HL/NHLBI NIH HHS/United States GR - KL2 TR000461/TR/NCATS NIH HHS/United States GR - R01 MD004113/MD/NIMHD NIH HHS/United States GR - 1KL2TR000461/TR/NCATS NIH HHS/United States PT - Journal Article PT - Research Support, N.I.H., Extramural DEP - 20150409 PL - England TA - Ann Med JT - Annals of medicine JID - 8906388 SB - IM MH - Black or African American/statistics & numerical data MH - Aged MH - Cross-Sectional Studies MH - Depression/diagnosis/epidemiology MH - Diabetes Complications/epidemiology/ethnology MH - Diabetes Mellitus/diagnosis/*epidemiology/ethnology MH - Female MH - Humans MH - Logistic Models MH - Male MH - Metabolic Syndrome/diagnosis/*epidemiology/ethnology MH - Middle Aged MH - Obesity/epidemiology MH - Outcome Assessment, Health Care MH - Risk Factors MH - Sleep Wake Disorders/diagnosis/*epidemiology/ethnology/metabolism MH - United States/epidemiology PMC - PMC4659349 MID - NIHMS738668 OTO - NOTNLM OT - Black race/ethnicity OT - diabetes mellitus OT - metabolic syndrome OT - sleep apnea COIS- Competing Interest/Disclosure Statement The authors declared no potential conflicts of interest with respect to the financial, research, authorship, and/or publication of this article. EDAT- 2015/04/10 06:00 MHDA- 2016/02/13 06:00 PMCR- 2015/11/25 CRDT- 2015/04/10 06:00 PHST- 2015/04/10 06:00 [entrez] PHST- 2015/04/10 06:00 [pubmed] PHST- 2016/02/13 06:00 [medline] PHST- 2015/11/25 00:00 [pmc-release] AID - 10.3109/07853890.2015.1015601 [doi] PST - ppublish SO - Ann Med. 2015 May;47(3):233-7. doi: 10.3109/07853890.2015.1015601. Epub 2015 Apr 9.