PMID- 25857933
OWN - NLM
STAT- MEDLINE
DCOM- 20151023
LR  - 20181113
IS  - 1880-6805 (Electronic)
IS  - 1880-6791 (Print)
IS  - 1880-6791 (Linking)
VI  - 34
IP  - 1
DP  - 2015 Mar 1
TI  - Brain activation during processing of angry facial expressions in patients with 
      alcohol dependency.
PG  - 6
LID - 10.1186/s40101-015-0046-6 [doi]
LID - 6
AB  - BACKGROUND: Alcoholism is associated with abnormal anger processing. The purpose 
      of this study was to investigate brain regions involved in the evaluation of 
      angry facial expressions in patients with alcohol dependency. METHODS: Brain 
      blood-oxygenation-level-dependent (BOLD) responses to angry faces were measured 
      and compared between patients with alcohol dependency and controls. RESULTS: 
      During intensity ratings of angry faces, significant differences in BOLD were 
      observed between patients with alcohol dependency and controls. That is, patients 
      who were alcohol-dependent showed significantly greater activation in several 
      brain regions, including the dorsal anterior cingulate cortex (dACC) and medial 
      prefrontal cortex (MPFC). CONCLUSIONS: Following exposure to angry faces, 
      abnormalities in dACC and MPFC activation in patients with alcohol dependency 
      indicated possible inefficiencies or hypersensitivities in social cognitive 
      processing.
FAU - Park, Mi-Sook
AU  - Park MS
FAU - Kim, Sook-Hee
AU  - Kim SH
FAU - Sohn, Sunju
AU  - Sohn S
FAU - Kim, Gap-Jung
AU  - Kim GJ
FAU - Kim, Yeon-Kyu
AU  - Kim YK
FAU - Sohn, Jin-Hun
AU  - Sohn JH
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20150301
PL  - England
TA  - J Physiol Anthropol
JT  - Journal of physiological anthropology
JID - 101269653
RN  - S88TT14065 (Oxygen)
SB  - IM
MH  - Adult
MH  - Alcoholism
MH  - Anger/*physiology
MH  - Brain/blood supply/*physiology
MH  - Brain Mapping
MH  - Face/physiology
MH  - *Facial Expression
MH  - Gyrus Cinguli/physiology
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Oxygen/blood
MH  - Prefrontal Cortex/physiology
PMC - PMC4350291
EDAT- 2015/04/11 06:00
MHDA- 2015/10/24 06:00
PMCR- 2015/03/01
CRDT- 2015/04/11 06:00
PHST- 2014/09/24 00:00 [received]
PHST- 2015/02/04 00:00 [accepted]
PHST- 2015/04/11 06:00 [entrez]
PHST- 2015/04/11 06:00 [pubmed]
PHST- 2015/10/24 06:00 [medline]
PHST- 2015/03/01 00:00 [pmc-release]
AID - s40101-015-0046-6 [pii]
AID - 46 [pii]
AID - 10.1186/s40101-015-0046-6 [doi]
PST - epublish
SO  - J Physiol Anthropol. 2015 Mar 1;34(1):6. doi: 10.1186/s40101-015-0046-6.