PMID- 25863093
OWN - NLM
STAT- MEDLINE
DCOM- 20150618
LR  - 20150412
IS  - 1003-9406 (Print)
IS  - 1003-9406 (Linking)
VI  - 32
IP  - 2
DP  - 2015 Apr
TI  - [Detection of chromosomal aneuploidies in spontaneous abortion samples by 
      fluorescence in situ hybridization].
PG  - 229-32
LID - 10.3760/cma.j.issn.1003-9406.2015.02.017 [doi]
AB  - OBJECTIVE: To analyze 81 spontaneous abortion samples with fluorescence in situ 
      hybridization (FISH). METHODS: Chromosome 13, 21, 16, 22, 18, X and Y probes were 
      used to detect the samples. RESULTS: FISH was successful in 80 cases (98.77%). 
      Among these, 35 (43.75%) had an abnormal karyotype, which included 19 autosomal 
      aneuploidies, 6 sex chromosome aneuploidies, 9 triploidies and 1 tetraploidy. 
      CONCLUSION: FISH is a rapid and easy method for detecting chromosomal 
      aneuploidies in spontaneous abortion samples, and has a higher detection rate in 
      early spontaneous abortion samples.
FAU - Wei, Ping
AU  - Wei P
AD  - Sichuan Provincial Maternal and Child Health Hospital, Chengdu, Sichuan 610041, 
      P.R. China. lyunxing2002@sina.cn.
FAU - Li, Yunxing
AU  - Li Y
FAU - Chen, Chun
AU  - Chen C
FAU - Zeng, Lan
AU  - Zeng L
FAU - Qin, Shengfang
AU  - Qin S
FAU - Wang, Xueyan
AU  - Wang X
FAU - Xi, Na
AU  - Xi N
LA  - chi
PT  - English Abstract
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - China
TA  - Zhonghua Yi Xue Yi Chuan Xue Za Zhi
JT  - Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese 
      journal of medical genetics
JID - 9425197
SB  - IM
MH  - Abortion, Spontaneous/diagnosis/*genetics
MH  - Adult
MH  - *Aneuploidy
MH  - Chromosome Aberrations
MH  - Chromosomes, Mammalian/*genetics
MH  - Female
MH  - Fetal Diseases/diagnosis/*genetics
MH  - Humans
MH  - In Situ Hybridization, Fluorescence
MH  - Male
MH  - Middle Aged
MH  - Pregnancy
MH  - Prenatal Diagnosis
MH  - Young Adult
EDAT- 2015/04/12 06:00
MHDA- 2015/06/19 06:00
CRDT- 2015/04/12 06:00
PHST- 2015/04/12 06:00 [entrez]
PHST- 2015/04/12 06:00 [pubmed]
PHST- 2015/06/19 06:00 [medline]
AID - 940632048 [pii]
AID - 10.3760/cma.j.issn.1003-9406.2015.02.017 [doi]
PST - ppublish
SO  - Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2015 Apr;32(2):229-32. doi: 
      10.3760/cma.j.issn.1003-9406.2015.02.017.