PMID- 25863241
OWN - NLM
STAT- MEDLINE
DCOM- 20150616
LR  - 20240316
IS  - 1932-7420 (Electronic)
IS  - 1550-4131 (Print)
IS  - 1550-4131 (Linking)
VI  - 21
IP  - 4
DP  - 2015 Apr 7
TI  - Hold the salt: vasopressor role for BDNF.
PG  - 509-10
LID - S1550-4131(15)00118-7 [pii]
LID - 10.1016/j.cmet.2015.03.015 [doi]
AB  - In a recent publication in Neuron, Choe et al. (2015) demonstrate that 
      brain-derived neurotrophic factor (BDNF) signaling mediates salt-induced blood 
      pressure elevation by increasing the excitability of hypothalamic 
      vasopressin-secreting neurons. These findings suggest complex roles for BDNF in 
      adaptive cardiovascular responses to physiological challenges and in the 
      pathogenesis of hypertension.
CI  - Copyright (c) 2015 Elsevier Inc. All rights reserved.
FAU - Marosi, Krisztina
AU  - Marosi K
AD  - Laboratory of Neurosciences, National Institute on Aging Intramural Research 
      Program, Baltimore, MD 21224, USA.
FAU - Mattson, Mark P
AU  - Mattson MP
AD  - Laboratory of Neurosciences, National Institute on Aging Intramural Research 
      Program, Baltimore, MD 21224, USA; Department of Neuroscience, Johns Hopkins 
      University School of Medicine, Baltimore, MD 21205, USA. Electronic address: 
      mark.mattson@nih.gov.
LA  - eng
GR  - Z99 AG999999/Intramural NIH HHS/United States
GR  - ZIA AG000312-11/Intramural NIH HHS/United States
GR  - ZIA AG000315-11/Intramural NIH HHS/United States
PT  - Comment
PT  - Journal Article
PT  - Research Support, N.I.H., Intramural
PL  - United States
TA  - Cell Metab
JT  - Cell metabolism
JID - 101233170
RN  - 0 (Brain-Derived Neurotrophic Factor)
RN  - 0 (Sodium Chloride, Dietary)
RN  - 0 (Symporters)
RN  - 11000-17-2 (Vasopressins)
SB  - IM
CON - Neuron. 2015 Feb 4;85(3):549-60. PMID: 25619659
MH  - Animals
MH  - Baroreflex/*physiology
MH  - Blood Pressure/*physiology
MH  - Brain-Derived Neurotrophic Factor/*pharmacology
MH  - Male
MH  - Sodium Chloride, Dietary/*adverse effects
MH  - Symporters/*metabolism
MH  - Vasopressins/*metabolism
PMC - PMC5840492
MID - NIHMS946974
EDAT- 2015/04/12 06:00
MHDA- 2015/06/17 06:00
PMCR- 2018/03/07
CRDT- 2015/04/12 06:00
PHST- 2015/04/12 06:00 [entrez]
PHST- 2015/04/12 06:00 [pubmed]
PHST- 2015/06/17 06:00 [medline]
PHST- 2018/03/07 00:00 [pmc-release]
AID - S1550-4131(15)00118-7 [pii]
AID - 10.1016/j.cmet.2015.03.015 [doi]
PST - ppublish
SO  - Cell Metab. 2015 Apr 7;21(4):509-10. doi: 10.1016/j.cmet.2015.03.015.