PMID- 25863860 OWN - NLM STAT- MEDLINE DCOM- 20151022 LR - 20161013 IS - 1715-3360 (Electronic) IS - 0008-4182 (Linking) VI - 50 IP - 2 DP - 2015 Apr TI - Natural course of vitreomacular traction syndrome observed by spectral-domain optical coherence tomography. PG - 172-9 LID - S0008-4182(14)00429-3 [pii] LID - 10.1016/j.jcjo.2014.12.003 [doi] AB - OBJECTIVE: Our study aimed to characterize the natural course of vitreomacular traction (VMT) syndrome, on which discrepancies have been reported in previous publications, by spectral-domain optical coherence tomography (SD-OCT). DESIGN: Retrospective chart review. PARTICIPANTS: A total of 23 eyes of 23 patients with idiopathic symptomatic VMT syndrome diagnosed and followed up in Peking Union Medical College Hospital from 2008 to 2013. METHODS: Clinical records of all patients who underwent SD-OCT examination and were diagnosed and followed up as idiopathic VMT syndrome were reviewed. Those who had at least 2 visits were included. The median observation period of the patients was 8.2 +/- 7.9 months. RESULTS: The 23 eyes were categorized into 3 groups based on the follow-up results of SD-OCT: the posterior vitreous detachment (PVD) group comprised 4 eyes that developed complete PVD, the full-thickness macular hole (FMH) group included 4 eyes that formed FMH, and the persisted VMT (PVMT) group comprised the other 15 eyes with PVMT. Epiretinal membrane (ERM) persisted in all 5 eyes in the PVMT group. FMH occurred in 3 of 7 eyes with outer lamellar macular hole (LMH) at the first visit. CONCLUSIONS: Spontaneous development of complete PVD in VMT syndrome during follow-up appeared to be more common in our study than in previous reports without SD-OCT. Persistence of ERM might be an unfavourable prognostic factor in the natural course of VMT syndrome. The outer LMH might be a risk factor for FMH formation. CI - Copyright (c) 2015 Canadian Ophthalmological Society. Published by Elsevier Inc. All rights reserved. FAU - Zhang, Zhiqiao AU - Zhang Z AD - Department of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China. Electronic address: zhangzhiqiao@sohu.com. FAU - Dong, Fangtian AU - Dong F AD - Department of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China. FAU - Zhao, Chan AU - Zhao C AD - Department of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China. FAU - Dai, Rongping AU - Dai R AD - Department of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China. FAU - Yu, Weihong AU - Yu W AD - Department of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China. FAU - Zheng, Lin AU - Zheng L AD - Department of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China. FAU - He, Feng AU - He F AD - Department of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China. FAU - Yang, Zhikun AU - Yang Z AD - Department of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China. LA - eng PT - Journal Article PL - England TA - Can J Ophthalmol JT - Canadian journal of ophthalmology. Journal canadien d'ophtalmologie JID - 0045312 SB - IM MH - Aged MH - Aged, 80 and over MH - Eye Diseases/*diagnosis MH - Female MH - Follow-Up Studies MH - Humans MH - Macula Lutea/pathology MH - Male MH - Middle Aged MH - Retinal Diseases/*diagnosis MH - Retinal Perforations/diagnosis MH - Retrospective Studies MH - Tissue Adhesions/diagnosis MH - *Tomography, Optical Coherence MH - Visual Acuity MH - Vitrectomy MH - Vitreous Body/*pathology MH - Vitreous Detachment/diagnosis EDAT- 2015/04/13 06:00 MHDA- 2015/10/23 06:00 CRDT- 2015/04/13 06:00 PHST- 2014/05/11 00:00 [received] PHST- 2014/11/10 00:00 [revised] PHST- 2014/12/10 00:00 [accepted] PHST- 2015/04/13 06:00 [entrez] PHST- 2015/04/13 06:00 [pubmed] PHST- 2015/10/23 06:00 [medline] AID - S0008-4182(14)00429-3 [pii] AID - 10.1016/j.jcjo.2014.12.003 [doi] PST - ppublish SO - Can J Ophthalmol. 2015 Apr;50(2):172-9. doi: 10.1016/j.jcjo.2014.12.003.