PMID- 25870627
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20150414
LR  - 20200929
IS  - 1735-5370 (Print)
IS  - 2008-2371 (Electronic)
IS  - 1735-5370 (Linking)
VI  - 9
IP  - 3
DP  - 2014
TI  - Mitral regurgitation after percutaneous balloon mitral valvotomy in patients with 
      rheumatic mitral stenosis: a single-center study.
PG  - 109-14
AB  - BACKGROUND: Percutaneous balloon mitral valvotomy (BMV) is the gold standard 
      treatment for rheumatic mitral stenosis (MS) in that it causes significant 
      changes in mitral valve area (MVA) and improves leaflet mobility. Development of 
      or increase in mitral regurgitation (MR) is common after BMV. This study 
      evaluated MR severity and its changes after BMV in Iranian patients. METHODS: We 
      prospectively evaluated consecutive patients with severe rheumatic MS undergoing 
      BMV using the Inoue balloon technique between February 2010 and January 2013 in 
      Madani Heart Center, Tabriz, Iran. New York Heart Association (NYHA) functional 
      class and echocardiographic and catheterization data, including MVA, mitral valve 
      mean and peak gradient (MVPG and MVMG), left atrial (LA) pressure, pulmonary 
      artery systolic pressure (PAPs), and MR severity before and after BMV, were 
      evaluated. RESULTS: Totally, 105 patients (80% female) at a mean age of 45.81 +/- 
      13.37 years were enrolled. NYHA class was significantly improved after BMV: 55.2% 
      of the patients were in NYHA functional class III before BMV compared to 36.2% 
      after the procedure (p value < 0.001). MVA significantly increased (mean area = 
      0.64 +/- 0.29 cm(2) before BMV vs. 1.90 +/- 0.22 cm(2) after BMV; p value < 0.001) 
      and PAPs, LA pressure, MVPG, and MVMG significantly decreased. MR severity did 
      not change in 82 (78.1%) patients, but it increased in 18 (17.1%) and decreased 
      in 5 (4.8%) patients. Patients with increased MR had a significantly higher 
      calcification score (2.03 +/- 0.53 vs.1.50 +/- 0.51; p value < 0.001) and lower MVA 
      before BMV (0.81 +/- 0.23 vs.0.94 +/- 0.18; p value = 0.010). There were no major 
      complications. CONCLUSION: In our study, BMV had excellent immediate hemodynamic 
      and clinical results inasmuch as MR severity increased only in some patients and, 
      interestingly, decreased in a few. Our results, underscore BMV efficacy in severe 
      MS. The echocardiographic calcification score was useful for identifying patients 
      likely to have MR development or MR increase after BMV.
FAU - Aslanabadi, Naser
AU  - Aslanabadi N
AD  - Department of Cardiology, Cardiovascular Research Center, Tabriz University of 
      Medical Sciences, Tabriz, Iran.
FAU - Toufan, Mehrnoush
AU  - Toufan M
AD  - Department of Cardiology, Cardiovascular Research Center, Tabriz University of 
      Medical Sciences, Tabriz, Iran.
FAU - Salehi, Rezvaneyeh
AU  - Salehi R
AD  - Department of Cardiology, Cardiovascular Research Center, Tabriz University of 
      Medical Sciences, Tabriz, Iran.
FAU - Alizadehasl, Azin
AU  - Alizadehasl A
AD  - Department of Cardiology, Cardiovascular Research Center, Tabriz University of 
      Medical Sciences, Tabriz, Iran.
FAU - Ghaffari, Samad
AU  - Ghaffari S
AD  - Department of Cardiology, Cardiovascular Research Center, Tabriz University of 
      Medical Sciences, Tabriz, Iran.
FAU - Sohrabi, Bahram
AU  - Sohrabi B
AD  - Department of Cardiology, Cardiovascular Research Center, Tabriz University of 
      Medical Sciences, Tabriz, Iran.
FAU - Separham, Ahmad
AU  - Separham A
AD  - Department of Cardiology, Cardiovascular Research Center, Tabriz University of 
      Medical Sciences, Tabriz, Iran.
FAU - Manafi, Ataolaah
AU  - Manafi A
AD  - Department of Cardiology, Cardiovascular Research Center, Tabriz University of 
      Medical Sciences, Tabriz, Iran.
FAU - Mehdizadeh, Mohammad Bagher
AU  - Mehdizadeh MB
AD  - Department of Cardiology, Cardiovascular Research Center, Tabriz University of 
      Medical Sciences, Tabriz, Iran.
FAU - Habibzadeh, Afshin
AU  - Habibzadeh A
AD  - Department of Cardiology, Cardiovascular Research Center, Tabriz University of 
      Medical Sciences, Tabriz, Iran.
LA  - eng
PT  - Journal Article
DEP - 20140703
PL  - Iran
TA  - J Tehran Heart Cent
JT  - The journal of Tehran Heart Center
JID - 101289255
PMC - PMC4393832
OTO - NOTNLM
OT  - Balloon volvuloplasty
OT  - Echocardiography
OT  - Mitral valve insufficiency
EDAT- 2014/01/01 00:00
MHDA- 2014/01/01 00:01
PMCR- 2014/01/01
CRDT- 2015/04/15 06:00
PHST- 2013/08/30 00:00 [received]
PHST- 2014/02/25 00:00 [accepted]
PHST- 2015/04/15 06:00 [entrez]
PHST- 2014/01/01 00:00 [pubmed]
PHST- 2014/01/01 00:01 [medline]
PHST- 2014/01/01 00:00 [pmc-release]
AID - jthc-9-109 [pii]
PST - ppublish
SO  - J Tehran Heart Cent. 2014;9(3):109-14. Epub 2014 Jul 3.