PMID- 25875945 OWN - NLM STAT- MEDLINE DCOM- 20160223 LR - 20181113 IS - 1861-0692 (Electronic) IS - 1861-0684 (Linking) VI - 104 IP - 6 DP - 2015 Jun TI - Gender differences in therapeutic recommendation after diagnostic coronary angiography: insights from the Coronary Angiography and PCI Registry of the German Society of Cardiology. PG - 507-17 LID - 10.1007/s00392-015-0815-6 [doi] AB - BACKGROUND: There is information suggesting differences and underuse of invasive coronary diagnostic and therapeutic procedures in women compared to men. METHODS: Data from consecutive patients (pts) which were enrolled in the Coronary Angiography and PCI Registry of the German Society of Cardiology were analyzed. We compared gender-related differences in diagnosis and therapeutic recommendation of pts undergoing coronary angiography (XA) for stable coronary artery disease (CAD), non-ST elevation acute coronary syndromes (NSTE-ACS) and ST elevation myocardial infarction (STEMI). RESULTS: From 2004 until the end of 2009, data of 1,060,542 invasive procedures in 1,014,996 pts were prospectively registered. One-third (34.6%) of them were female. Women less often had significant CAD, irrespective of the indication for XA. In pts with relevant CAD, percutaneous coronary interventions (PCI) were recommended in 87.1% of women versus 89.1% of men with STEMI [age-adjusted OR (aOR) 0.98, 95% CI 0.93-1.04], in 67.1 vs. 66.8% in NSTE-ACS (aOR 1.10, 1.07-1.12), and in 50.3 vs 49.4% in stable CAD (aOR 1.07, 1.05-1.09). CONCLUSIONS: In pts with significant CAD, there was no difference in recommendation for PCI between the genders in stable CAD, whereas in STEMI and NSTE-ACS women were treated even more often with PCI. There were only minor differences in referral for CABG between women and men. Hence, our data provide strong evidence against a gender bias in use of invasive therapeutic procedures once the diagnosis of significant CAD has been confirmed. FAU - Heer, Tobias AU - Heer T AD - Department of Cardiology, Krankenhaus Agatharied, Academic Teaching Hospital, University of Munich, Norbert-Kerkel-Platz, 83607, Hausham, Germany, tobias.heer@khagatharied.de. FAU - Hochadel, Matthias AU - Hochadel M FAU - Schmidt, Karin AU - Schmidt K FAU - Mehilli, Julinda AU - Mehilli J FAU - Zahn, Ralf AU - Zahn R FAU - Kuck, Karl-Heinz AU - Kuck KH FAU - Hamm, Christian AU - Hamm C FAU - Bohm, Michael AU - Bohm M FAU - Ertl, Georg AU - Ertl G FAU - Andresen, Dietrich AU - Andresen D FAU - Massberg, Steffen AU - Massberg S FAU - Senges, Jochen AU - Senges J FAU - Pilz, Gunter AU - Pilz G FAU - Gitt, Anselm K AU - Gitt AK FAU - Zeymer, Uwe AU - Zeymer U LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20150121 PL - Germany TA - Clin Res Cardiol JT - Clinical research in cardiology : official journal of the German Cardiac Society JID - 101264123 SB - IM MH - Acute Coronary Syndrome/*diagnosis/epidemiology/surgery MH - Aged MH - Coronary Angiography/*methods MH - Coronary Artery Disease/*diagnosis/epidemiology/surgery MH - Female MH - Germany MH - Healthcare Disparities/statistics & numerical data MH - Humans MH - Male MH - Middle Aged MH - Myocardial Infarction/*diagnosis/epidemiology/surgery MH - Percutaneous Coronary Intervention/statistics & numerical data MH - Prospective Studies MH - Registries MH - Sex Factors EDAT- 2015/04/16 06:00 MHDA- 2016/02/26 06:00 CRDT- 2015/04/16 06:00 PHST- 2014/12/15 00:00 [received] PHST- 2015/01/13 00:00 [accepted] PHST- 2015/04/16 06:00 [entrez] PHST- 2015/04/16 06:00 [pubmed] PHST- 2016/02/26 06:00 [medline] AID - 10.1007/s00392-015-0815-6 [doi] PST - ppublish SO - Clin Res Cardiol. 2015 Jun;104(6):507-17. doi: 10.1007/s00392-015-0815-6. Epub 2015 Jan 21.