PMID- 25882098
OWN - NLM
STAT- MEDLINE
DCOM- 20151204
LR  - 20220310
IS  - 1872-7123 (Electronic)
IS  - 0165-1781 (Linking)
VI  - 227
IP  - 2-3
DP  - 2015 Jun 30
TI  - Relationships between global assessment of functioning and other rating scales in 
      clinical trials for schizophrenia.
PG  - 265-9
LID - S0165-1781(15)00153-5 [pii]
LID - 10.1016/j.psychres.2015.02.024 [doi]
AB  - The relationship between the Global Assessment of Functioning (GAF) with other 
      scales in schizophrenia has rarely been investigated. A systematic literature 
      search was conducted to identify articles that reported the GAF score together 
      with scores in the Positive and Negative Syndrome Scale (PANSS), Clinical Global 
      Impression (CGI) or Brief Psychiatric Rating Scale (BPRS), using MEDLINE, EMBASE 
      and PsycINFO, with keywords of schizophrenia, clinical trial and global 
      assessment of functioning (last search 30 June 2013). Correlational analyses with 
      weighting by the study participant numbers across these rating scales were 
      performed. In 40 clinical trials (n=8000) that reported cross-sectional data on 
      the GAF and PANSS, a significant but modest correlation was noted (Pearson׳s 
      r=-0.401, p<0.0001). Furthermore, a correlation between the GAF and CGI-severity 
      (CGI-S) at study baseline in 38 studies (n=11,315) was robust (r=-0.893, 
      p<0.0001). In longitudinal studies, changes in the GAF scores were negatively 
      correlated with those in the PANSS as well as CGI-S scores (p<0.0001 for both). 
      Data on the BPRS were all statistically significant although relatively scarce. 
      While optimal degree of concordance is undetermined among psychiatric scales that 
      are presumed to be measuring different but overlapping constructs, this study 
      found significant correlations in the GAF and CGI-S or PANSS, both 
      cross-sectionally and longitudinally. The GAF-CGI-S relationship was especially 
      tighter, making it a reliable clinical indicator.
CI  - Copyright (c) 2015 Elsevier Ireland Ltd. All rights reserved.
FAU - Suzuki, Takefumi
AU  - Suzuki T
AD  - Department of Neuropsychiatry, Keio University, School of Medicine, Tokyo, Japan; 
      Department of Psychiatry, Inokashira Hospital, Tokyo, Japan. Electronic address: 
      takefumi@oak.dti.ne.jp.
FAU - Uchida, Hiroyuki
AU  - Uchida H
AD  - Department of Neuropsychiatry, Keio University, School of Medicine, Tokyo, Japan; 
      Centre for Addiction and Mental Health, Geriatric Mental Health Program, Toronto, 
      Ontario, Canada.
FAU - Sakurai, Hitoshi
AU  - Sakurai H
AD  - Department of Neuropsychiatry, Keio University, School of Medicine, Tokyo, Japan; 
      Department of Psychiatry, Inokashira Hospital, Tokyo, Japan.
FAU - Ishizuki, Tomomi
AU  - Ishizuki T
AD  - Department of Neuropsychiatry, Keio University, School of Medicine, Tokyo, Japan; 
      Department of Psychiatry, Kawasaki City Rehabilitation Medical Center, Kanagawa, 
      Japan.
FAU - Tsunoda, Kenichi
AU  - Tsunoda K
AD  - Department of Neuropsychiatry, Keio University, School of Medicine, Tokyo, Japan; 
      Department of Psychiatry, Minami Hannou Hospital, Saitama, Japan.
FAU - Takeuchi, Hiroyoshi
AU  - Takeuchi H
AD  - Department of Neuropsychiatry, Keio University, School of Medicine, Tokyo, Japan; 
      Centre for Addiction and Mental Health, Schizophrenia Program, Toronto, Ontario, 
      Canada.
FAU - Mimura, Masaru
AU  - Mimura M
AD  - Department of Neuropsychiatry, Keio University, School of Medicine, Tokyo, Japan.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20150401
PL  - Ireland
TA  - Psychiatry Res
JT  - Psychiatry research
JID - 7911385
SB  - IM
MH  - Brief Psychiatric Rating Scale/standards
MH  - Clinical Trials as Topic/*standards
MH  - Cross-Sectional Studies
MH  - Humans
MH  - Longitudinal Studies
MH  - Psychiatric Status Rating Scales/*standards
MH  - Schizophrenia/*diagnosis/epidemiology
OTO - NOTNLM
OT  - Clinical global impression
OT  - Global assessment of functioning
OT  - Outcome
OT  - Positive and negative syndrome scale
OT  - Schizophrenia
EDAT- 2015/04/18 06:00
MHDA- 2015/12/15 06:00
CRDT- 2015/04/18 06:00
PHST- 2014/07/12 00:00 [received]
PHST- 2014/11/26 00:00 [revised]
PHST- 2015/02/13 00:00 [accepted]
PHST- 2015/04/18 06:00 [entrez]
PHST- 2015/04/18 06:00 [pubmed]
PHST- 2015/12/15 06:00 [medline]
AID - S0165-1781(15)00153-5 [pii]
AID - 10.1016/j.psychres.2015.02.024 [doi]
PST - ppublish
SO  - Psychiatry Res. 2015 Jun 30;227(2-3):265-9. doi: 10.1016/j.psychres.2015.02.024. 
      Epub 2015 Apr 1.